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NCT02119624 · ClinicalTrials.gov registry record
Neural Substrates of Approach-Avoidance Conflict
A clinical trial of Alcoholism and fMRI, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- Completed
- Registry status
- 62
- Enrollment target
- 1
- Study location
NCT02119624: Completed study of Alcoholism and fMRI, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
NCT02119624 is a study of Alcoholism and fMRI that has completed, run by National Institute on Alcohol Abuse and Alcoholism (NIAAA). The registered enrollment target is 62 participants, below the 374-participant average among 65 other Alcoholism trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02119624, a study of Alcoholism and fMRI, has completed, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- COMPLETED
- Registry status
- 62 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- People who are dependent on alcohol drink even when they know something bad might happen. Researchers want to learn more about why they do this. Objectives: \- To study brain response when a person plays a game in different threat conditions. Eligibility: * Healthy right-handed adult heavy drinkers age 21 60 * Healthy right-handed adult light drinkers age 21 60 Design: * Participants will be screened with medical history, physical exam, and blood and urine tests. They will have an EKG and psychiatric interview. * Participants will have one or two clinic visits. * Participants will be asked about their alcohol drinking. * They will choose a snack and alcoholic beverage that they must drink in 5 minutes. After their breath alcohol content (BrAC) is zero, they will play a game in the MRI scanner. * The scanner is a metal cylinder that takes pictures of the brain. Participants lie on a table that slides in and out of the cylinder. They will be in it for about 90 minutes, lying still for up to 20 minutes. * During the MRI, participants will play a simple computer game to earn food or drink points under different threats of electric shock. Points can be exchanged for food or alcohol after the game. Sometimes, participants will receive a mild electric shock through a metal disk on the wrist. Electric shocks will only happen if the participant tries to earn a reward point. * After the MRI, participants use their points for another drink and snack. They will stay at the clinic until their BrAC is low, usually within 3 hours. Participants cannot drive themselves home. * Participants will have a follow-up phone call the next day.
Primary Outcome
fMRI and behavioral differences between light drinkers and heavy drinkers.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2014-07-23 |
| Est. Completion | 2020-09-01 |
What the finished NCT02119624 record still lists
NCT02119624 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 374-participant average among 65 other Alcoholism trials with a reported enrollment target (83% lower).
The record links to 3 conditions, with Alcoholism appearing as the primary indexed condition, and to 0 interventions.
NCT02119624 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT02119624 about?
NCT02119624 is a clinical study titled "Neural Substrates of Approach-Avoidance Conflict". Background: \- People who are dependent on alcohol drink even when they know something bad might happen. Researchers want to learn more about why they do this. Objectives: \- To study brain response when a person plays a game in different threat conditions. Eligibility: * Healthy right-handed a...
What is the current status of trial NCT02119624?
This trial is currently completed. The enrollment target is 62 participants. The study started on 2014-07-23. Estimated completion is 2020-09-01.
What conditions does trial NCT02119624 study?
This clinical trial studies the following conditions: Alcoholism, fMRI, Rewarding Mediating System.
Who is sponsoring clinical trial NCT02119624?
This trial is sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02119624 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02119624's enrollment target sits among peer trials
62 47th of 65 higher than 19 of 65 other Alcoholism trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcoholism trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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