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NCT06361095 · ClinicalTrials.gov registry record · Early Phase 1
Confirmatory Efficacy Trial of Attention Bias Modification for Depression
A Early Phase 1 study of Depression, sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 600
- Enrollment target
- 1
- Study location
NCT06361095: Recruiting Early Phase 1 study of Depression, sponsored by University of Texas at Austin.
NCT06361095 is a Early Phase 1 study of Depression that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 600 participants, below the 785-participant average among 679 other Depression trials with a reported enrollment target (24% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06361095, a Early Phase 1 study of Depression, is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to compare the efficacy of two related, but different ABM (Attention Biased Modification) treatments for depression in adults with elevated symptoms of depression. The main aims are: * Aim 1:examine whether gamified ABM leads to greater change in the primary and secondary outcomes than sham ABM * Aim 1: establish that gamified ABM is at least as effective as traditional ABM. * Aim 2: identify moderators of ABM efficacy and mechanisms responsible for its efficacy. * Aim 3: Identify the durability of ABM on depression symptoms during short-term follow-up Participants will complete self-report questionnaires, complete eye-tracking tasks, and be clinically assessed through interviews by clinician researchers. If there is a comparison group: Researchers will compare sham, traditional, and gamified treatment groups to see if they moderate symptoms of depression.
Primary Outcome
The Quick Inventory of Depressive Symptoms (QIDS) is a 16-item measure (self-report and clinician-rated versions) for adults with depression with solid psychometric properties and substantial data supporting sensitivity to change. The QIDS assesses the criterion domains used to diagnose a major depressive disorder. The participant must score a minimum of 13 on the QIDS-SR at the baseline assessment to qualify for participation. Total QIDS scores range from 0 to 27, with higher scores reflecting
Conditions Studied
Interventions
- BEHAVIORAL Traditional Attention Bias Modification
- BEHAVIORAL Gamified Attention Bias Modification
- BEHAVIORAL Sham Attention Bias Modification
Study Locations (1)
Texas
- Institute for Mental Health Research - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2024-05-01 |
| Est. Completion | 2028-05-01 |
| Phase | Early Phase 1 |
What NCT06361095 shows while recruiting
NCT06361095 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 679 other Depression trials with a reported enrollment target (24% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 3 interventions - of which Traditional Attention Bias Modification is the first listed.
NCT06361095 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06361095 about?
NCT06361095 is a clinical study titled "Confirmatory Efficacy Trial of Attention Bias Modification for Depression". The goal of this clinical trial is to compare the efficacy of two related, but different ABM (Attention Biased Modification) treatments for depression in adults with elevated symptoms of depression. The main aims are: * Aim 1:examine whether gamified ABM leads to greater change in the primary and s...
What is the current status of trial NCT06361095?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 600 participants. The study started on 2024-05-01. Estimated completion is 2028-05-01.
What conditions does trial NCT06361095 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT06361095?
The interventions under investigation include: Traditional Attention Bias Modification (BEHAVIORAL), Gamified Attention Bias Modification (BEHAVIORAL), Sham Attention Bias Modification (BEHAVIORAL).
Who is sponsoring clinical trial NCT06361095?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06361095 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06361095's enrollment target sits among peer trials
600 68th of 679 higher than 612 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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