Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
OCD clinical trials
Every US clinical trial registered for OCD — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
19 US clinical trials · 13 currently recruiting
The research picture
OCD has 19 registered US clinical trials, 13 of them open to new participants right now — about 68% of the total.
- 13
- recruiting participants now
- 68%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Yale University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
Neuronetics
NCT06997549
Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings
Bradley Hospital
NCT06934525
Discovering Factors in the Clinical Study Journey of Patients With OCD
Power Life Sciences
NCT05881356
Accelerated TMS for Depression and OCD
Weill Medical College of Cornell University
NCT04982757
Neurostimulation Versus Therapy for Problems With Emotions
Duke University
NCT05712057
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Yale University
NCT06624137
How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD
University of Pennsylvania
NCT05359562
Neuromodulation for a Novel OCD Biomarker and Treatment
Boston University Charles River Campus
NCT05994053
Multi-session, Personalized Cognitive Bias Modification for Thought-Action-Fusion
Han Joo Lee
NCT06731426
Paired tVNS With ERP in OCD
University of Florida
NCT05580614
Open-Label Psilocybin Study in Transdiagnostic Population
Yale University
NCT06442423
Light Therapy for Obsessive-compulsive Disorder (OCD)
Washington University School of Medicine
NCT06720090
Personalized DBS for OCD Guided by Stereoencephalography Mapping
Andrew Moses Lee, MD, PhD
NCT06347978
Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder
Stanford University
NCT03511534
A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder
University of Chicago
NCT05624528
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
Baylor College of Medicine
NCT03459456
Testing a Transdiagnostic TMS Treatment Target
Brigham and Women's Hospital
NCT06282146
Development of an Instrument That Monitors Behaviors Associated With OCD
University of Minnesota
NCT02866422
Rapid Non-Invasive Brain Stimulation for OCD (oTMS)
Stanford University
NCT03404609
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the OCD Trial Landscape
ClinicalTrials.gov lists 19 US studies indexed under OCD, and 13 of those are currently open to recruitment — roughly 68% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for OCD shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for OCD is led by Yale University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for OCD?
PlainTrial tracks 19 US clinical trials for OCD, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for OCD?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.