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ClinicalTrials.gov 13 recruiting now official registry

OCD clinical trials

Every US clinical trial registered for OCD — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

19 US clinical trials · 13 currently recruiting

The research picture

OCD has 19 registered US clinical trials, 13 of them open to new participants right now — about 68% of the total.

13
recruiting participants now
68%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Yale University

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 12,000 participants

Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments

Neuronetics

NCT06997549

RECRUITING NA 501 participants

Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings

Bradley Hospital

NCT06934525

RECRUITING 500 participants

Discovering Factors in the Clinical Study Journey of Patients With OCD

Power Life Sciences

NCT05881356

RECRUITING NA 500 participants

Accelerated TMS for Depression and OCD

Weill Medical College of Cornell University

NCT04982757

RECRUITING NA 240 participants

Neurostimulation Versus Therapy for Problems With Emotions

Duke University

NCT05712057

RECRUITING 200 participants

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

NCT06624137

RECRUITING NA 120 participants

How Hormones and Exposure and Response Prevention (EX/RP) Affect the Brain of People With OCD

University of Pennsylvania

NCT05359562

RECRUITING NA 90 participants

Neuromodulation for a Novel OCD Biomarker and Treatment

Boston University Charles River Campus

NCT05994053

RECRUITING NA 84 participants

Multi-session, Personalized Cognitive Bias Modification for Thought-Action-Fusion

Han Joo Lee

NCT06731426

RECRUITING NA 56 participants

Paired tVNS With ERP in OCD

University of Florida

NCT05580614

RECRUITING Phase 1 50 participants

Open-Label Psilocybin Study in Transdiagnostic Population

Yale University

NCT06442423

RECRUITING Early Phase 1 40 participants

Light Therapy for Obsessive-compulsive Disorder (OCD)

Washington University School of Medicine

NCT06720090

RECRUITING NA 10 participants

Personalized DBS for OCD Guided by Stereoencephalography Mapping

Andrew Moses Lee, MD, PhD

NCT06347978

ACTIVE NOT RECRUITING NA 200 participants

Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder

Stanford University

NCT03511534

ACTIVE NOT RECRUITING Phase 2 49 participants

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

University of Chicago

NCT05624528

ACTIVE NOT RECRUITING 27 participants

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)

Baylor College of Medicine

NCT03459456

ACTIVE NOT RECRUITING Early Phase 1 10 participants

Testing a Transdiagnostic TMS Treatment Target

Brigham and Women's Hospital

NCT06282146

COMPLETED 40 participants

Development of an Instrument That Monitors Behaviors Associated With OCD

University of Minnesota

NCT02866422

COMPLETED NA 7 participants

Rapid Non-Invasive Brain Stimulation for OCD (oTMS)

Stanford University

NCT03404609

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the OCD Trial Landscape

ClinicalTrials.gov lists 19 US studies indexed under OCD, and 13 of those are currently open to recruitment — roughly 68% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for OCD shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for OCD is led by Yale University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 19 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for OCD?

PlainTrial tracks 19 US clinical trials for OCD, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for OCD?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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