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NCT07189585 · ClinicalTrials.gov registry record · Phase 2
Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis
A Phase 2 study, sponsored by Yale University.
- Not yet
- Registry status
- Phase 2
- Development phase
- 84
- Enrollment target
NCT07189585: Clinical Trial Phase 2 study, sponsored by Yale University.
NCT07189585 is a Phase 2 study that has not yet begun recruiting, run by Yale University. The registered enrollment target is 84 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07189585, a Phase 2 study, has not yet begun recruiting, sponsored by Yale University.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 84 participants
- Enrollment target
Study Summary
This study will test whether inulin, a type of dietary fiber, can reduce inflammation in older adults with knee osteoarthritis. Inflammation in the body may contribute to both joint pain and the progression of osteoarthritis. Inulin is a prebiotic fiber that may improve gut health and reduce lipopolysaccharide (LPS), a marker of bacterial products in the blood that is linked to inflammation. In this trial, participants with knee osteoarthritis will be randomly assigned to receive either inulin or a placebo (maltodextrin) for 8 weeks. The study will measure changes in blood LPS levels, knee pain, and other markers of inflammation. The goal is to determine whether inulin supplementation can improve pain and reduce inflammation in people with knee osteoarthritis.
Primary Outcome
Serum LPS levels will be measured at baseline and at 8 weeks to evaluate the effect of inulin supplementation compared to placebo.
Interventions
- DRUG Maltodextrin (Placebo)
- DRUG inulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2026-11-01 |
| Est. Completion | 2027-07-31 |
| Phase | Phase 2 |
What is known before NCT07189585 opens enrollment
NCT07189585 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (37% lower).
The record links to 0 conditions, and to 2 interventions - of which Maltodextrin (Placebo) is the first listed.
NCT07189585 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07189585 about?
NCT07189585 is a clinical study titled "Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis". This study will test whether inulin, a type of dietary fiber, can reduce inflammation in older adults with knee osteoarthritis. Inflammation in the body may contribute to both joint pain and the progression of osteoarthritis. Inulin is a prebiotic fiber that may improve gut health and reduce lipopol...
What is the current status of trial NCT07189585?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 84 participants. The study started on 2026-11-01. Estimated completion is 2027-07-31.
What interventions are being tested in trial NCT07189585?
The interventions under investigation include: Maltodextrin (Placebo) (DRUG), inulin (DRUG).
Who is sponsoring clinical trial NCT07189585?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07189585's enrollment target sits among peer trials
84 822nd of 2000 higher than 1,173 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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