Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 30 of 30

COMPLETED NA

Family-Centered Behavioral Preparation for Surgery

NCT00261261

COMPLETED

Age Related Changes in Calciotropic Hormones and Their Impact on Male Osteoporosis

NCT00588874

COMPLETED Phase 2

Disulfiram for Cocaine Abuse in Buprenorphine Treatment

NCT00913484

COMPLETED NA

Framing Messages for Smoking Cessation With Bupropion - 6

NCT00104598

COMPLETED

Detection of Ischemia in Asymptomatic Diabetics

NCT00769275

COMPLETED Phase 2

Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1

NCT00023283

COMPLETED NA

Cognitive Training and Enhanced Supported Employment in Schizophrenia

NCT00339170

COMPLETED Phase 2

Repetitive Transcranial Magnetic Stimulation for "Voices"

NCT00004980

COMPLETED

Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children

NCT01967849

COMPLETED NA

Comparison of Two Surgical Treatments for Necrotizing Enterocolitis in Human Infants

NCT00252681

COMPLETED Phase 1

Docetaxel and Irinotecan in Treating Patients With Advanced Solid Tumors

NCT00004923

COMPLETED Phase 2

Paclitaxel and Irinotecan in Treating Patients With Advanced Non-small Cell Lung Cancer

NCT00004924

COMPLETED Phase 2

Relational Parenting Group for Opioid-addicted Mothers

NCT00319241

COMPLETED NA

Glycine and Oral D-Cycloserine in Alcoholic Patients and Healthy Subjects

NCT00635102

COMPLETED Phase 2

Combination Chemotherapy Followed by Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancer

NCT00003111

TERMINATED Phase 1

High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

NCT00002948

TERMINATED Phase 1

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

NCT00002947

COMPLETED Phase 1

Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer

NCT00002950

COMPLETED Phase 2

Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2

NCT00000319

COMPLETED Phase 4

Naltrexone Treatment for Alcoholic Women

NCT00000448

COMPLETED Phase 2

Aminocamptothecin in Treating Patients With T-cell Lymphoma

NCT00002635

COMPLETED Phase 3

Combining Behavioral Treatment With Agonist Maintenance - 1

NCT00000311

COMPLETED Phase 2

Behavioral Treatment for Cocaine Dependent Women

NCT00914381

COMPLETED Phase 2

Disulfiram for Cocaine-Alcohol Abuse - 3

NCT00000278

COMPLETED Phase 2

Pemoline for Cocaine Abuse - 7

NCT00000282

COMPLETED Phase 2

Novel Medications for Opiate Detoxification - 4

NCT00000279

COMPLETED Phase 2

Pharmacotherapy for Schizophrenic Drug Users - 6

NCT00000281

COMPLETED Phase 2

Mazindol for Cocaine Abuse - 2

NCT00000277

COMPLETED Phase 1

Glutaminergic Agents for Cocaine Abuse - 5

NCT00000280

TERMINATED Phase 1

Dopamine Reuptake Inhibitors of Cocaine Abuse - 1

NCT00000276

COMPLETED Phase 2

Adjuvant High-Dose, Sequential Chemotherapy in Treating Patients With Resected Breast Cancer

NCT00002679

COMPLETED Phase 2

Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer

NCT00002680

COMPLETED Phase 2

Rapid Benzodiazepine Detoxification Using Flumazenil - 1

NCT00000246

COMPLETED Phase 3

Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer

NCT00002507

COMPLETED Phase 3

Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial

NCT00033917

COMPLETED Phase 2

Buprenorphine Maintenance for Opioid Addicts - 3

NCT00000204

COMPLETED Phase 2

Buprenorphine Maintenance for Opioid Addicts - 1

NCT00000202

COMPLETED Phase 2

Buprenorphine Maintenance for Opioid Addicts - 2

NCT00000203

COMPLETED Phase 3

Levetiracetam Treatment of Tardive Dyskinesia

NCT00291213

COMPLETED Phase 4

Smoking Cessation in Alcoholism Treatment

NCT00000454

COMPLETED Phase 2

Acamprosate Treatment: Mechanisms of Action

NCT00004552

COMPLETED Phase 3

Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1

NCT00000216

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.