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NCT00002680 · ClinicalTrials.gov registry record · Phase 2
Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer
A Phase 2 study, sponsored by Yale University.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT00002680: Completed Phase 2 study, sponsored by Yale University.
NCT00002680 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002680, a Phase 2 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of sequential high-dose chemotherapy followed by peripheral stem cell transplantation in treating patients with metastatic breast cancer that is responding to chemotherapy.
Interventions
- DRUG cyclophosphamide
- DRUG melphalan
- BIOLOGICAL filgrastim
- DRUG tamoxifen citrate
- DRUG megestrol acetate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 1994-02 |
| Est. Completion | 2000-12 |
| Phase | Phase 2 |
What the finished NCT00002680 record still lists
NCT00002680 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.
NCT00002680 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00002680 about?
NCT00002680 is a clinical study titled "Sequential High-Dose Chemotherapy and Stem Cell Transplantation in Treating Patients With Chemotherapy-Sensitive Metastatic Breast Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of sequential high-dose chemotherapy...
What is the current status of trial NCT00002680?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 1994-02. Estimated completion is 2000-12.
What interventions are being tested in trial NCT00002680?
The interventions under investigation include: cyclophosphamide (DRUG), melphalan (DRUG), filgrastim (BIOLOGICAL), tamoxifen citrate (DRUG), megestrol acetate (DRUG).
Who is sponsoring clinical trial NCT00002680?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00002680's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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