Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00004552 · ClinicalTrials.gov registry record · Phase 2

Acamprosate Treatment: Mechanisms of Action

A Phase 2 study, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
120
Enrollment target

NCT00004552: Completed Phase 2 study, sponsored by Yale University.

NCT00004552 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 120 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00004552, a Phase 2 study, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
120 participants
Enrollment target

Study Summary

This study will examine whether pretreatment with two doses of acamprosate for seven days prior to abstinence lessens the intensity of acute withdrawal from alcohol compared with a placebo. Subjects will be randomly assigned to receive either one of two doses of acamprosate or placebo for seven days. This will be followed by a four- day inpatient period when withdrawal will be monitored. Additional drinking information will be obtained at a three month followup interview.

Interventions

  • DRUG acamprosate (Campral)

Trial Details

FieldValue
Enrollment Target 120 participants
Est. Completion 2002-12
Phase Phase 2
Yale University

1,492 total trials

What the finished NCT00004552 record still lists

NCT00004552 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower).

The record links to 0 conditions, and to 1 intervention - of which acamprosate (Campral) is the first listed.

NCT00004552 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00004552 about?

NCT00004552 is a clinical study titled "Acamprosate Treatment: Mechanisms of Action". This study will examine whether pretreatment with two doses of acamprosate for seven days prior to abstinence lessens the intensity of acute withdrawal from alcohol compared with a placebo. Subjects will be randomly assigned to receive either one of two doses of acamprosate or placebo for seven days...

What is the current status of trial NCT00004552?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 120 participants. Estimated completion is 2002-12.

What interventions are being tested in trial NCT00004552?

The interventions under investigation include: acamprosate (Campral) (DRUG).

Who is sponsoring clinical trial NCT00004552?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00004552's enrollment target sits among peer trials

120 569th of 2000 higher than 1,383 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01174108 · 120 participants · Phase 2

    Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

  • NCT01627301 · 120 participants · NA

    Sympathetic Overactivity in Post-traumatic Stress Disorder

  • NCT02025023 · 120 participants · Phase 3

    Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

  • NCT02128906 · 120 participants · Phase 2

    Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Source: ClinicalTrials.gov NCT00004552, the US trial registry maintained by the National Library of Medicine. NCT00004552 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.