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NCT02979977 · ClinicalTrials.gov registry record · Phase 2

Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

A Phase 2 study, sponsored by Yale University.

Completed
Registry status
Phase 2
Development phase
50
Enrollment target

NCT02979977 is a Phase 2 study that has completed, run by Yale University. The registered enrollment target is 50 participants.

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The verdict

NCT02979977, a Phase 2 study, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 2
Development phase
50 participants
Enrollment target

Study Summary

This is a single arm Phase II study for patients with recurrent or metastatic squamous cell carcinoma of the head and neck, who are previously treated with a platinum based regimen or with an immune checkpoint inhibitor. The primary objective is to evaluate the efficacy of the combination of cetuximab and afatinib.

Interventions

  • DRUG cetuximab
  • DRUG afatinib

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2017-03-24
Est. Completion 2026-01-18
Phase Phase 2

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT02979977

The ClinicalTrials.gov registry entry for NCT02979977 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which cetuximab is the first listed.

NCT02979977 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02979977 about?

NCT02979977 is a clinical study titled "Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck". This is a single arm Phase II study for patients with recurrent or metastatic squamous cell carcinoma of the head and neck, who are previously treated with a platinum based regimen or with an immune checkpoint inhibitor. The primary objective is to evaluate the efficacy of the combination of cetuxim...

What is the current status of trial NCT02979977?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2017-03-24. Estimated completion is 2026-01-18.

What interventions are being tested in trial NCT02979977?

The interventions under investigation include: cetuximab (DRUG), afatinib (DRUG).

Who is sponsoring clinical trial NCT02979977?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.