Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 11 of 30

COMPLETED NA

Follicular Revival in Androgenic Alopecia: Evaluating Use of Micro-needling

NCT04341363

COMPLETED NA

Follicular Revival in Treatment-resistant Alopecia Areata: Evaluating Use of Micro-needling

NCT04338295

COMPLETED

Autism Biomarker Consortium for Clinical Trials (ABC-CT): Follow-up Study

NCT04841525

COMPLETED NA

Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling

NCT04342091

TERMINATED Phase 4

Targeting the Gut-brain Axis to Facilitate Weight Loss in High Fat Diet Consumers

NCT04614233

COMPLETED NA

Parent Training for Youth With Chronic Symptoms

NCT04277715

COMPLETED

Respiratory Supports and COVID-19 Mortality

NCT04832061

COMPLETED NA

Quit Nicotine: E-Cig Cessation Intervention

NCT04898075

COMPLETED Phase 1

CYstic Fibrosis bacterioPHage Study at Yale (CYPHY)

NCT04684641

COMPLETED Phase 1

Evaluating the Safety, Tolerability, Pharmacokinetics and Receptor Occupancy of BMS-984923

NCT04805983

COMPLETED NA

Stimulation Therapy for Inducing Mothers

NCT04756089

COMPLETED NA

Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention

NCT04760652

COMPLETED Phase 2

A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

NCT04457310

COMPLETED NA

A Digital Intervention to Prevent Initiation of Opioid Misuse in Adolescents in School-based Health Centers

NCT04109599

COMPLETED Phase 1

Inhibition of Sterile Inflammation by Digoxin

NCT03559868

COMPLETED NA

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

NCT04561765

COMPLETED NA

Behavioral Weight Loss Treatment for Individuals With Food Addiction

NCT04311450

COMPLETED

Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department

NCT04846322

COMPLETED Phase 3

Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure

NCT05093621

COMPLETED NA

Mindful Kala: Virtual Bharatanatyam Wellness Program for Students

NCT04745364

COMPLETED Early Phase 1

Mindfulness-Based ADHD Treatment for Children: a Feasibility Study

NCT04737512

COMPLETED

Gocheck Kids vs. Welch Allyn Spot Vision Screener

NCT04321538

COMPLETED

Investigating Stress-related Mechanisms in the Laboratory and Real World in Individuals With Cannabis Use Disorder

NCT04116619

COMPLETED Phase 1

GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight

NCT04779697

COMPLETED NA

Pragmatic Trial of Messaging to Providers About Treatment of Heart Failure

NCT04514458

COMPLETED NA

Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU

NCT04652453

COMPLETED NA

COVID-19 Responsive Intervention: Systems Improvement Simulations (CRI:SIS)

NCT04614844

COMPLETED NA

Effects of Hepatic Ultrasound on Metabolic Homeostasis

NCT04622683

COMPLETED

Continuous Non-invasive Hemodynamic Monitoring in Early-onset Severe Preeclampsia: a Comparison of Echocardiography, Bioreactance, and Finger Cuff Measurements

NCT05299229

COMPLETED NA

Parental Guidance for Failure to Launch.

NCT04704583

TERMINATED Phase 2

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

NCT04575610

COMPLETED Phase 1

Pharmacokinetics and Hepatic Safety of EGCG

NCT04177693

COMPLETED NA

Smartband Mindfulness Study

NCT03995225

COMPLETED NA

Perinatal Attentional Retraining Intervention for Smoking for Minority Women

NCT04114877

TERMINATED NA

The Effect of Lactation on Insulin Sensitivity and Lipolysis in Women

NCT04146909

COMPLETED NA

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

NCT04306341

COMPLETED Phase 1

The Interaction of Flavor With Nicotine Form in Adult Smokers

NCT04262817

COMPLETED Phase 2

Combining Varenicline and Guanfacine for Smoking Cessation

NCT04198116

COMPLETED Phase 2

Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.

NCT04345341

COMPLETED NA

Song-making In a Group (SING) R61

NCT05537428

COMPLETED Phase 3

Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial

NCT04472611

TERMINATED Phase 2

Tofacitinib for Treatment of Moderate COVID-19

NCT04415151

COMPLETED NA

vDPP Facilitated With Community Care Coordination

NCT04195477

COMPLETED NA

Cognitive-Behavioral Therapy for Weight-related Bullying (Online Treatment)

NCT04587752

COMPLETED NA

Assessing Mental Health Providers' Clinical Knowledge and Skills Via an Online Training on LGBTQ-affirmative Cognitive-behavioral Therapy

NCT04559698

COMPLETED NA

Being Present With Art: The Impact of Mindful Engagement With Art on Awareness and Connection

NCT04722367

TERMINATED Early Phase 1

FAAH Availability in Psychiatric Disorders: A PET Study

NCT04404712

COMPLETED NA

Evaluating Efficacy of Digital Health Technology in the Treatment of Congestive Heart Failure

NCT04394754

COMPLETED NA

An Intervention to Correct Dualistic Reasoning About the Effectiveness of Psychotherapy for Biologically Caused Mental Disorders

NCT05800119

COMPLETED

Variation in Opioid Prescribing and Use for Acute Pain in Diverse Populations

NCT04509115

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.