Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04116619 · ClinicalTrials.gov registry record

Investigating Stress-related Mechanisms in the Laboratory and Real World in Individuals With Cannabis Use Disorder

A clinical trial, sponsored by Yale University.

Completed
Registry status
39
Enrollment target

NCT04116619: Completed study, sponsored by Yale University.

NCT04116619 is a clinical trial that has completed, run by Yale University. The registered enrollment target is 39 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04116619 has completed, sponsored by Yale University.

COMPLETED
Registry status
39 participants
Enrollment target

Study Summary

This research project proposes a novel approach to elucidate the biological adaptations associated with Cannabis Use Disorder and to assess whether such adaptations are predictive of higher drug craving in response to both drug cues and stressors in both the laboratory and real-world, and higher relapse risk and drug use in the real world.

Primary Outcome

Participants will rate their level of stress and marijuana craving at five time points during the laboratory session, once at pre-baseline, baseline, immediately post-imagery procedures, and at three times point 15, 30, and 45 minutes post-imagery. Craving and stress will be assessed using a 100-point visual analog scale (VAS) in which 0="Not at all" and 100="Extremely High." Individuals with CUD will be compared to light marijuana users in their differences in slope in response to the imagery.

Interventions

  • OTHER Guided Imagery Laboratory Session

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2021-02-01
Est. Completion 2022-02-01
Yale University

1,492 total trials

What the finished NCT04116619 record still lists

NCT04116619 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 39 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Guided Imagery Laboratory Session is the first listed.

NCT04116619 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04116619 about?

NCT04116619 is a clinical study titled "Investigating Stress-related Mechanisms in the Laboratory and Real World in Individuals With Cannabis Use Disorder". This research project proposes a novel approach to elucidate the biological adaptations associated with Cannabis Use Disorder and to assess whether such adaptations are predictive of higher drug craving in response to both drug cues and stressors in both the laboratory and real-world, and higher rel...

What is the current status of trial NCT04116619?

This trial is currently completed. The enrollment target is 39 participants. The study started on 2021-02-01. Estimated completion is 2022-02-01.

What interventions are being tested in trial NCT04116619?

The interventions under investigation include: Guided Imagery Laboratory Session (OTHER).

Who is sponsoring clinical trial NCT04116619?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03465592 · 39 participants · Phase 1

    Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

  • NCT03961776 · 39 participants

    Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems

  • NCT04050280 · 39 participants · Phase 2

    CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

  • NCT04190862 · 39 participants · Phase 1

    E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04116619, the US trial registry maintained by the National Library of Medicine. NCT04116619 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.