Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04832061 · ClinicalTrials.gov registry record
Respiratory Supports and COVID-19 Mortality
A clinical trial of COVID-19, sponsored by Yale University.
- Completed
- Registry status
- 2,300
- Enrollment target
- 1
- Study location
NCT04832061 is a study of COVID-19 that has completed, run by Yale University. The registered enrollment target is 2,300 participants, below the 55,203-participant average among 203 other COVID-19 trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04832061, a study of COVID-19, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- 2,300 participants
- Enrollment target
- 1
- Study location
Study Summary
Critically ill COVID-19 patients have a relatively high mortality rate (\~30%). Most critically ill COVID-19 patients require respiratory supports. The respiratory supports used in this patient population included conventional oxygen therapy (COT) via nasal cannula or face mask, non-invasive ventilation (NIV), and invasive mechanical ventilation (IMV). NIV has three different methods, including high-flow nasal cannula (HFNC), bilevel positive airway pressure (BiPAP), and continuous positive airway pressure (CPAP). There are outstanding questions that remain to be answered. One is which NIV is more effective; the other is if the use of IMV leads to increased mortality. Another relevant question is if ventilator settings (such as tidal volume, drive pressure, and positive end-expiratory pressure) are associated with different mechanical ventilated patients' outcomes. To answer these questions, a retrospective cohort study based on all patients who had been treated in the ICUs in Yale New Haven Health System throughout the first pandemic year was designed.
Conditions Studied
Interventions
- OTHER Respiratory supports
Study Locations (1)
Connecticut
- Yale University School of Medicine - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,300 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2021-04-20 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04832061
The ClinicalTrials.gov registry entry for NCT04832061 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 2,300 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 55,203-participant average among 203 other COVID-19 trials with a reported enrollment target (96% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with COVID-19 appearing as the primary indexed condition, and to 1 intervention - of which Respiratory supports is the first listed.
NCT04832061 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT04832061 about?
NCT04832061 is a clinical study titled "Respiratory Supports and COVID-19 Mortality". Critically ill COVID-19 patients have a relatively high mortality rate (\~30%). Most critically ill COVID-19 patients require respiratory supports. The respiratory supports used in this patient population included conventional oxygen therapy (COT) via nasal cannula or face mask, non-invasive ventila...
What is the current status of trial NCT04832061?
This trial is currently completed. The enrollment target is 2,300 participants. The study started on 2021-04-01. Estimated completion is 2021-04-20.
What conditions does trial NCT04832061 study?
This clinical trial studies the following conditions: COVID-19.
What interventions are being tested in trial NCT04832061?
The interventions under investigation include: Respiratory supports (OTHER).
Who is sponsoring clinical trial NCT04832061?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04832061 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for COVID-19
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19
RECRUITING · NA
-
Arginine Replacement Therapy in COVID-19
RECRUITING · Phase 2
-
A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
RECRUITING · Phase 2
-
Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors
RECRUITING
-
COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise
RECRUITING
-
The Impact of COVID-19 on Maternal and Neonatal Outcomes
RECRUITING
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.