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NCT04622709 · ClinicalTrials.gov registry record · Phase 2
Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis
A Phase 2 study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- Phase 2
- Development phase
- 39
- Enrollment target
NCT04622709 is a Phase 2 study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 39 participants.
The verdict
NCT04622709, a Phase 2 study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 39 participants
- Enrollment target
Study Summary
Individuals with kidney failure receiving maintenance hemodialysis (HD) have high mortality rates, driven largely by cardiovascular causes. Volume-related factors are critical, modifiable contributors to cardiovascular complications. Reversing volume overload has been shown to improve blood pressure and cardiac remodeling. Use of loop diuretics may represent a pragmatic, low-cost, and low-burden strategy to improve outcomes in people receiving HD. Lack of data on optimal furosemide dosing, safety, and acceptability are barriers to expanded use. This study investigates whether oral furosemide is safe and effective at increasing urine volume in HD patients.
Interventions
- DRUG Furosemide (loop diuretic) Tablets
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2020-10-07 |
| Est. Completion | 2021-06-22 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04622709
The ClinicalTrials.gov registry entry for NCT04622709 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 39 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Furosemide (loop diuretic) Tablets is the first listed.
NCT04622709 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04622709 about?
NCT04622709 is a clinical study titled "Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis". Individuals with kidney failure receiving maintenance hemodialysis (HD) have high mortality rates, driven largely by cardiovascular causes. Volume-related factors are critical, modifiable contributors to cardiovascular complications. Reversing volume overload has been shown to improve blood pressure...
What is the current status of trial NCT04622709?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2020-10-07. Estimated completion is 2021-06-22.
What interventions are being tested in trial NCT04622709?
The interventions under investigation include: Furosemide (loop diuretic) Tablets (DRUG).
Who is sponsoring clinical trial NCT04622709?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
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