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NCT04207333 · ClinicalTrials.gov registry record · NA
Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT04207333: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT04207333 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04207333, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
Prolonged sitting may pose a public health risk through its effects on the cardiovascular system, and may lead to impaired whole-body cardiovascular health, which includes both vascular and cerebrovascular function. These effects may interact with other environmental variables, such as stress. However, no study has investigated the combined effect of a mental stressor and prolonged sitting on vascular and cerebrovascular function. The combined effect of prolonged sitting and mental stress may lead to an exacerbated effect on vascular, cerebrovascular, and executive function. The investigators hypothesize that mental stress with the addition of prolonged sitting \[PS\] will result in a greater increase in peripheral, central and cerebral arterial stiffness and elicit a decrease in cerebral perfusion, total blood flow to the brain, middle cerebral artery velocity and executive function, compared to mental stress without prolonged sitting \[CON\]. The findings from this study may result in a public health message regarding sedentary behavior and stress, and will help elucidate the mechanisms behind acute vascular, cerebrovascular, and cognitive dysfunction during prolonged sitting.
Primary Outcome
bfPWV (m/s) is the velocity at which a pressure wave travels between the brachial and femoral arterial segments. An increase in bfPWV represents increased arterial stiffness (worse outcome).
Interventions
- BEHAVIORAL Mental Arithmetic Test
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2020-01-11 |
| Est. Completion | 2020-06-01 |
| Phase | NA |
What the finished NCT04207333 record still lists
NCT04207333 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Mental Arithmetic Test is the first listed.
NCT04207333 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04207333 about?
NCT04207333 is a clinical study titled "Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System". Prolonged sitting may pose a public health risk through its effects on the cardiovascular system, and may lead to impaired whole-body cardiovascular health, which includes both vascular and cerebrovascular function. These effects may interact with other environmental variables, such as stress. Howev...
What is the current status of trial NCT04207333?
This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2020-01-11. Estimated completion is 2020-06-01.
What interventions are being tested in trial NCT04207333?
The interventions under investigation include: Mental Arithmetic Test (BEHAVIORAL).
Who is sponsoring clinical trial NCT04207333?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04207333's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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