Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04423627 · ClinicalTrials.gov registry record · Early Phase 1
Sympathetic Regulation of Large Artery Stiffness in Humans With ISH
A Early Phase 1 study, sponsored by University of Iowa.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 100
- Enrollment target
NCT04423627 is a Early Phase 1 study that has completed, run by University of Iowa. The registered enrollment target is 100 participants.
The verdict
NCT04423627, a Early Phase 1 study, has completed, sponsored by University of Iowa.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 100 participants
- Enrollment target
Study Summary
Stiffening of your blood vessels, particularly the large vessels from your heart (called the aorta and carotids) you age contributes to the development of cardiovascular disease (CVD) such as heart attack and stroke. Nerve activity from your brain to your body also increases with advancing age but it is unknown if this nerve activity contributes directly to the stiffening on your blood vessels in older adults in addition to high blood pressure. Therefore, successful completion of the proposed aims will have a significant clinical impact by identifying if nerve activity from your brain could be a novel target for therapies that would lower stiffness of the aorta and carotid arteries in older adults.
Interventions
- DRUG Placebo
- DRUG Clonidine
- DRUG Hydrochlorothiazide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-06-01 |
| Est. Completion | 2025-07-31 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04423627
The ClinicalTrials.gov registry entry for NCT04423627 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Iowa, which has 228 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT04423627 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04423627 about?
NCT04423627 is a clinical study titled "Sympathetic Regulation of Large Artery Stiffness in Humans With ISH". Stiffening of your blood vessels, particularly the large vessels from your heart (called the aorta and carotids) you age contributes to the development of cardiovascular disease (CVD) such as heart attack and stroke. Nerve activity from your brain to your body also increases with advancing age but i...
What is the current status of trial NCT04423627?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 100 participants. The study started on 2021-06-01. Estimated completion is 2025-07-31.
What interventions are being tested in trial NCT04423627?
The interventions under investigation include: Placebo (DRUG), Clonidine (DRUG), Hydrochlorothiazide (DRUG).
Who is sponsoring clinical trial NCT04423627?
This trial is sponsored by University of Iowa, which has 228 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.