Rush University Medical Center

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Rush University Medical Center sits in the top decile of US sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count).

320 total trials 53 currently recruiting 206 completed top decile by trial count

Rush University Medical Center: 320 sponsored US clinical trials, 53 recruiting.

Rush University Medical Center sponsors 320 registered US clinical trials on ClinicalTrials.gov, 53 of them currently recruiting, and 206 completed. 42 of these trials are in Phase 3-4 (later-stage) and 41 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Total Knee Arthroplasty, with 3 trials.

Top-decile sponsor footprint

Rush University Medical Center ranks in the top decile of sponsors by registered trial count (#112 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 51/100

206 of 244 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (84.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

320 total, page 6 of 7

COMPLETED Phase 2

Use of a Novel Fibrin Sealant in Total Knee Arthroplasty

NCT01656759

COMPLETED NA

Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation

NCT01778712

COMPLETED NA

Lifestyle Improvement Through Food and Exercise (LIFE)Study

NCT01901952

COMPLETED NA

Hub Cleansing to Prevent Hub Infection

NCT01563406

COMPLETED Phase 4

Eszopiclone for the Treatment of Posttraumatic Stress Disorder

NCT01605253

COMPLETED Phase 4

Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep

NCT01695863

COMPLETED NA

Circadian Phase Assessments at Home

NCT01487252

COMPLETED NA

Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection

NCT01373112

COMPLETED

Effect of Ischemic Strokes on Recovery From Intracerebral Hemorrhages

NCT01417117

COMPLETED NA

Study of Antibiotic Spacer Design to Treat Infection After Hip Replacement

NCT01373099

COMPLETED NA

Hyaluronic Acid vs Platelet Rich Plasma: Effects on Clinical Outcomes and Intra-articular Biology for the Treatment of Knee Osteoarthritis

NCT02588872

COMPLETED NA

Mind-Body Medicine and Ulcerative Colitis

NCT01491997

COMPLETED

Study on Immunopathogenesis in HIV and Hepatitis C Coinfection

NCT01296529

COMPLETED NA

Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee Arthroplasty

NCT01760863

COMPLETED Phase 4

Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients With Severe Kidney Disease Undergoing Myocardial Perfusion Imaging

NCT01336140

COMPLETED NA

Combined Social Worker and Pharmacist Transitional Care Program

NCT01503554

TERMINATED Phase 4

Carbohydrate Consumption as a Factor in Aspart Dosing

NCT01333514

COMPLETED

Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement

NCT01320150

COMPLETED NA

Reducing Disparities in Late Life Depression and Metabolic Syndrome

NCT01428791

TERMINATED Phase 2

A Trial of Lenalidomide & Azacitidine in Low Risk Myelodysplastic Syndromes

NCT01379274

COMPLETED Phase 2

Varenicline for Gait and Balance Impairment in Parkinson Disease

NCT01341080

COMPLETED Phase 4

Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy

NCT02058693

COMPLETED

Endoscopic Size Assessment of Advanced Adenomatous Polyps

NCT02193646

TERMINATED Phase 4

Study With Aminophylline to Attenuate of the Side Effects of Regadenoson

NCT01250496

COMPLETED Phase 4

Dilute Betadine Lavage in the Prevention of Postoperative Infection

NCT01175044

COMPLETED Phase 4

Effect of Prophylactic Antibiotics on Intra-Operative Culture Results

NCT01174212

COMPLETED NA

Coping Peer Intervention for Adherence

NCT01169883

COMPLETED NA

Women's Walking Program

NCT01700894

COMPLETED Phase 4

Validation of Dyskinesia Rating Scales

NCT01071395

COMPLETED NA

The Community United to Challenge Asthma

NCT01061424

COMPLETED NA

The Community United to Challenge Asthma

NCT01065883

COMPLETED NA

Enhanced Discharge Planning Program -- Prospective

NCT01378234

COMPLETED Phase 4

Study of the Effect of Fluticasone Furoate Nasal Spray on Spring Allergy Eye Symptoms

NCT00891436

COMPLETED NA

Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties

NCT00834483

COMPLETED

Interleukin (IL)-13 as a Marker in Pediatrics Asthma

NCT00968305

COMPLETED Phase 2

Mindfulness-Based Approaches to Insomnia

NCT00768781

TERMINATED Phase 4

Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV Disease

NCT00775606

TERMINATED NA

Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine

NCT00737139

COMPLETED Phase 2

Self-Management in African Americans With Diabetes and Hypertension

NCT01244152

COMPLETED Phase 4

Management of Diabetes in the Emergency Room: a Randomized Trial of an Insulin Protocol.

NCT00591227

COMPLETED NA

Sleep Length and Circadian Regulation in Humans

NCT00843843

COMPLETED Phase 3

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

NCT00559819

COMPLETED Phase 2

Safety and Effectiveness Study of a Fiber Supplement for Weight Loss

NCT00613600

COMPLETED Phase 1

Ranibizumab for Treatment of Persistent Diabetic Neovascularization Assessed by Wide-Field Imaging

NCT00606138

COMPLETED Phase 4

Study to Evaluate the Safety and Efficacy of Alefacept (Amevive) in Subjects With Moderate to Severe Atopic Dermatitis

NCT00832585

COMPLETED Phase 1

Mind/Body Medicine and IBD Flare-Up

NCT00568256

COMPLETED NA

Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints

NCT00597376

COMPLETED

Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease

NCT01155492

COMPLETED Phase 4

Metformin for the Prevention of the Metabolic Side-effects of Zyprexa

NCT00682448

COMPLETED NA

The Effects of Specialized Footwear in Osteoarthritis

NCT01597830

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Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 25
Phase 3 6
Phase 4 36

What is open in the Rush University Medical Center pipeline

53 recruiting of 320 indexed (17% open); 206 completed (64%).

Phase mix: 42 late (III/IV) vs 41 early (I/II) (balanced across stages).

Top condition: Total Knee Arthroplasty (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Rush University Medical Center: open-pipeline peers nationwide

Peers matched on 320 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 0%5%10%15%20% Total trials Recruiting share Rush University Medical CenterJonsson Comprehensive Cancer CenterUniversity of ArkansasAllerganGenentechOHSU Knight Cancer InstituteMassachusetts General HospitalAdageneAgendia
Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Rush University Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 320 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Rush University Medical Center page

320 registered trials is a research-attention snapshot, not an endorsement of Rush University Medical Center or any single study.

  • 53 of Rush University Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Total Knee Arthroplasty is the condition Rush University Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Total Knee Arthroplasty trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Rush University Medical Center pipeline card: 320 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.