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NCT00597376 · ClinicalTrials.gov registry record · NA
Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints
A NA study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 104
- Enrollment target
NCT00597376: Completed NA study, sponsored by Rush University Medical Center.
NCT00597376 is a NA study that has completed, run by Rush University Medical Center. The registered enrollment target is 104 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00597376, a NA study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 104 participants
- Enrollment target
Study Summary
The purpose of this six-month research study is to determine if Cerefolin NAC reduces levels of substances in the blood that may be associated with thinking ability and the health of brain cells in subjects with memory concerns when compared to a standard multivitamin. Cerefolin NAC is available as a dietary supplement via a prescription from a physician. The multivitamin used in the study contains the Recommended Daily Intake recommended for older persons.
Primary Outcome
Primary outcome markers were plasma homocysteine (tHcy), glutathione, and the ratio of amyloid proteins, Aβ42 and Aβ40. Plasma tHcy and glutathione were assayed using a high performance liquid chromatography (HPLC) with fluorescence detection method. Enzyme-linked immunosorbent assays (ELISA) were used for Aβ42 (Wako Chemicals USA, Inc., Richmond, VA) and Aβ40 (Invitrogen Corporation, Canarillo, CA) detection. Primary analyses utilized Last Observation Carried Forward (LOCF) to assess the primar
Interventions
- OTHER Cerefolin NAC (a medical food)
- OTHER Cerefolin NAC placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104 participants |
| Start Date | 2007-11 |
| Est. Completion | 2011-05 |
| Phase | NA |
What the finished NCT00597376 record still lists
NCT00597376 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Cerefolin NAC (a medical food) is the first listed.
NCT00597376 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00597376 about?
NCT00597376 is a clinical study titled "Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints". The purpose of this six-month research study is to determine if Cerefolin NAC reduces levels of substances in the blood that may be associated with thinking ability and the health of brain cells in subjects with memory concerns when compared to a standard multivitamin. Cerefolin NAC is available as ...
What is the current status of trial NCT00597376?
This trial is currently completed. It is a NA study. The enrollment target is 104 participants. The study started on 2007-11. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00597376?
The interventions under investigation include: Cerefolin NAC (a medical food) (OTHER), Cerefolin NAC placebo (OTHER).
Who is sponsoring clinical trial NCT00597376?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00597376's enrollment target sits among peer trials
104 836th of 2000 higher than 1,164 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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