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NCT01250496 · ClinicalTrials.gov registry record · Phase 4

Study With Aminophylline to Attenuate of the Side Effects of Regadenoson

A Phase 4 study, sponsored by Rush University Medical Center.

Terminated
Registry status
Phase 4
Development phase
248
Enrollment target

NCT01250496: Clinical Trial Phase 4 study, sponsored by Rush University Medical Center.

NCT01250496 is a Phase 4 study that was terminated before completion, run by Rush University Medical Center. The registered enrollment target is 248 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01250496, a Phase 4 study, was terminated before completion, sponsored by Rush University Medical Center.

TERMINATED
Registry status
Phase 4
Development phase
248 participants
Enrollment target

Study Summary

The routine administration of 75 mg of intravenous aminophylline following regadenoson (Lexiscan®), a commonly used medication for nuclear stress testing of the heart, can reduce the gastrointestinal (diarrhea and stomach upset) and other side effects related to regadenoson.

Primary Outcome

Patients will be surveyed for these symptoms following to the completion of the cardiac stress testing procedure and prior to discharge from the laboratory.

Interventions

  • DRUG Placebo
  • DRUG Aminophylline

Trial Details

FieldValue
Enrollment Target 248 participants
Start Date 2010-11
Est. Completion 2011-11
Phase Phase 4
Rush University Medical Center

320 total trials

Why NCT01250496 stopped before completion

NCT01250496 is an interventional study that assigns participants to a tested intervention. The registered 248 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (52% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01250496 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01250496 about?

NCT01250496 is a clinical study titled "Study With Aminophylline to Attenuate of the Side Effects of Regadenoson". The routine administration of 75 mg of intravenous aminophylline following regadenoson (Lexiscan®), a commonly used medication for nuclear stress testing of the heart, can reduce the gastrointestinal (diarrhea and stomach upset) and other side effects related to regadenoson.

What is the current status of trial NCT01250496?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 248 participants. The study started on 2010-11. Estimated completion is 2011-11.

What interventions are being tested in trial NCT01250496?

The interventions under investigation include: Placebo (DRUG), Aminophylline (DRUG).

Who is sponsoring clinical trial NCT01250496?

This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01250496's enrollment target sits among peer trials

248 353rd of 2000 higher than 1,646 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01250496, the US trial registry maintained by the National Library of Medicine. NCT01250496 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.