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NCT00834483 · ClinicalTrials.gov registry record · NA
Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties
A NA study, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 65
- Enrollment target
NCT00834483: Completed NA study, sponsored by Rush University Medical Center.
NCT00834483 is a NA study that has completed, run by Rush University Medical Center. The registered enrollment target is 65 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00834483, a NA study, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 65 participants
- Enrollment target
Study Summary
Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time. The purpose of this study is to evaluate the use of Quill as part of our layered closure compared to using our traditional sutures. The study timeline begins at the time of the surgical procedure and continues through the routine follow-up of total joint replacements at 2, 6, and 12 weeks, and will conclude at the six month post-operative office visit. Primary Objectives: * To evaluate the safety and efficacy of wound closure in primary hip and knee replacements using a bidirectional barbed suture (knotless) compared to a traditional layered (vicryl) wound closure. Secondary Objectives: * Establish the all around (intra-operative and post-operative) cost-savings potential in using a knotless wound closure compared to that of a layered vicryl closure (our standard suture protocol). * Assess the overall cosmesis of the wound/scar as well as perceived presence of subcutaneous surgical knots, when using the knotless wound closure versus our traditional layered suture closure.
Primary Outcome
We performed a prospective, randomized clinical trial to evaluate the efficacy of using a bidirectional barbed suture compared with traditional sutures in the deep closure of primary total hip (25) and knee (35) arthroplasties. Complications, time to closure, and length of surgery were evaluated.
Interventions
- DEVICE Knotless suture for wound closure
- DEVICE Layered traditional wound closure (monocryl)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2009-02 |
| Est. Completion | 2012-12 |
| Phase | NA |
What the finished NCT00834483 record still lists
NCT00834483 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Knotless suture for wound closure is the first listed.
NCT00834483 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00834483 about?
NCT00834483 is a clinical study titled "Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties". Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time. The purpose of this study is to evaluate the use of Quill as part of our layered closur...
What is the current status of trial NCT00834483?
This trial is currently completed. It is a NA study. The enrollment target is 65 participants. The study started on 2009-02. Estimated completion is 2012-12.
What interventions are being tested in trial NCT00834483?
The interventions under investigation include: Knotless suture for wound closure (DEVICE), Layered traditional wound closure (monocryl) (DEVICE).
Who is sponsoring clinical trial NCT00834483?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00834483's enrollment target sits among peer trials
65 1144th of 2000 higher than 854 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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