Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02588872 · ClinicalTrials.gov registry record · NA
Hyaluronic Acid vs Platelet Rich Plasma: Effects on Clinical Outcomes and Intra-articular Biology for the Treatment of Knee Osteoarthritis
A NA study of Osteoarthritis, Knee, sponsored by Rush University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 111
- Enrollment target
- 1
- Study location
NCT02588872: Completed NA study of Osteoarthritis, Knee, sponsored by Rush University Medical Center.
NCT02588872 is a NA study of Osteoarthritis, Knee that has completed, run by Rush University Medical Center. The registered enrollment target is 111 participants, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02588872, a NA study of Osteoarthritis, Knee, has completed, sponsored by Rush University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 111 participants
- Enrollment target
- 1
- Study location
Study Summary
In this, prospective, double-blind study, patients with mild to moderate symptomatic knee osteoarthritis will be randomized to receive either a series of leukocyte poor, platelet-rich plasma or hyaluronic acid injections under ultrasound guidance. Clinical data in the form of subjective outcome measures will be collected pre-treatment and at four time intervals across a 1-year period. Synovial fluid will also collected for analysis of pro- and anti-inflammatory markers pre-treatment, and at 12 and 24 weeks.
Primary Outcome
This is a scale from 1-100, 100 being high function and 1 being very poor function that will be assessed via paper questionnaire at the delineated time intervals. The Primary outcome assessed will be at an average of 1-year post treatment.
Conditions Studied
Interventions
- BIOLOGICAL Platelet-rich Plasma (PRP)
- BIOLOGICAL Hyaluronic Acid
Study Locations (1)
Illinois
- Rush University Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 111 participants |
| Start Date | 2011-08 |
| Est. Completion | 2015-04 |
| Phase | NA |
What the finished NCT02588872 record still lists
NCT02588872 is an interventional study that assigns participants to a tested intervention. The registered 111 participants enrollment target is mid-sized for trials with a published cap, below the 497-participant average among 112 other Osteoarthritis, Knee trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Osteoarthritis, Knee appearing as the primary indexed condition, and to 2 interventions - of which Platelet-rich Plasma (PRP) is the first listed.
NCT02588872 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT02588872 about?
NCT02588872 is a clinical study titled "Hyaluronic Acid vs Platelet Rich Plasma: Effects on Clinical Outcomes and Intra-articular Biology for the Treatment of Knee Osteoarthritis". In this, prospective, double-blind study, patients with mild to moderate symptomatic knee osteoarthritis will be randomized to receive either a series of leukocyte poor, platelet-rich plasma or hyaluronic acid injections under ultrasound guidance. Clinical data in the form of subjective outcome meas...
What is the current status of trial NCT02588872?
This trial is currently completed. It is a NA study. The enrollment target is 111 participants. The study started on 2011-08. Estimated completion is 2015-04.
What conditions does trial NCT02588872 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee.
What interventions are being tested in trial NCT02588872?
The interventions under investigation include: Platelet-rich Plasma (PRP) (BIOLOGICAL), Hyaluronic Acid (BIOLOGICAL).
Who is sponsoring clinical trial NCT02588872?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02588872 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis, Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02588872's enrollment target sits among peer trials
111 62nd of 112 higher than 51 of 112 other Osteoarthritis, Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis, Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Mobilizing Hispanics With Knee Osteoarthritis
RECRUITING · NA
-
Physica System Total Knee Replacement Registry Study
RECRUITING · NA
-
The Osteoarthritis Prevention Study
RECRUITING · NA
-
Navio Robotic Versus Conventional Total Knee Arthroplasty
RECRUITING · NA
-
MOTION Clinical Trial
RECRUITING · NA
-
Radio- KO Radiotherapy for Knee Osteoarthritis Clinical Trial
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03875716 · 111 participants · NA
Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma
- NCT04693468 · 111 participants · Phase 1
Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial
- NCT05263050 · 111 participants · Phase 2
Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors
- NCT05600842 · 111 participants
De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia