National Institute on Drug Abuse (NIDA)
National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.
Trial Pipeline
335 total, page 6 of 7
Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Disorder - 5
NCT00015223
Buprenorphine Detoxification - BBDVI - 19
NCT00000237
Stress Hormones and Human Cocaine Use - 7
NCT00000290
Tyrosine for Methamphetamine Dependence - 1
NCT00000322
Modeling Impaired Judgement in Cocaine Abusers - 6
NCT00015236
The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1
NCT00158288
Tryptophan and Behavior Therapy for Cocaine Abuse - 1
NCT00000324
Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9
NCT00000274
Phase II Double-Blind, Placebo-Controlled Study of the Reinforcing Effects of Alprazolam in Patients With Anxiety
NCT00004373
Prepulse Inhibition of Startle in Cocaine Dependence - 7
NCT00015249
Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users
NCT00158236
Cocaine Effects in Humans: Physiology and Behavior - 1
NCT00000200
Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3
NCT00000286
Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1
NCT00000352
Buprenorphine and Naloxone Combination Study - 10
NCT00015288
Cocaine Abuse and ADHD - 10
NCT00000275
Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2
NCT00015041
Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1
NCT00015028
Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1
NCT00000315
Trial of Buprenorphine/Naloxone for Opiate Dependence - 2
NCT00000353
Methamphetamine Abuse Treatment in Patients With AIDS - 1
NCT00000321
Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2
NCT00000316
Evaluation of Liquid vs. Tablet Buprenorphine - 6
NCT00000341
Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence
NCT00134914
Therapeutic Potential of Kappa-Opioids Against Cocaine - 1
NCT00000323
Risperidone for the Treatment of Cocaine Dependence - 7
NCT00000342
Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3
NCT00000354
Effects of Phenytoin on Cocaine Use in Humans - 2
NCT00000285
Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1
NCT00015171
Acute Withdrawal From Smoked Cocaine - 9
NCT00000292
Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10
NCT00000345
Brain Changes in Stimulant Dependent Subjects - 8
NCT00000343
Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2
NCT00000310
Role of Metabolites in Nicotine Dependence (2) - 5
NCT00000288
Pergolide Treatment for Substance Abusers - 4
NCT00000269
Activity Monitoring Assessment of Opiate Withdrawal - 4
NCT00000335
Dextroamphetamine-Cocaine Behavioral Intervention - 5
NCT00000308
Buprenorphine Combination Tablet Feasibility - 1
NCT00000298
Cocaine Abuse and Attention Deficit Disorder - 3
NCT00000268
Naltrexone in Treatment of Cocaine Dependence - 5
NCT00015080
Role of Metabolites in Nicotine Dependence (1) - 1
NCT00000284
Relapse Patterns in Female Cocaine Users - 4
NCT00000287
Selegiline in Outpatient Treatment for Cocaine Dependence - 1
NCT00000336
Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1
NCT00000318
Alternate-Day Buprenorphine Administration. Phase VII - 8
NCT00000226
Infusion Laboratory: Protocol 1 - Selegeline - 2
NCT00000337
Effects of Buprenorphine and Naloxone in Opiate Addicts - 4
NCT00000355
M-CPP and Fenfluramine in Cocaine Addicts - 3
NCT00000314
Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3
NCT00000306
Flupenthixol Treatment in Schizophrenic Cocaine Abusers - 1
NCT00000266
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 81 |
| Phase 2 | 121 |
| Phase 3 | 14 |
| Phase 4 | 16 |
What the Pipeline for National Institute on Drug Abuse (NIDA) Shows
According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.
The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.