National Institute on Drug Abuse (NIDA)

335 total trials 14 currently recruiting 292 completed

National Institute on Drug Abuse (NIDA) sponsors 335 registered US clinical trials on ClinicalTrials.gov, 14 of them currently recruiting, and 292 completed. 30 of these trials are in Phase 3-4 (later-stage) and 202 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cocaine-Related Disorders, with 17 trials.

Trial Pipeline

335 total, page 7 of 7

COMPLETED Phase 2

Buprenorphine Detox With Two Types of Treatment. BBD I - 10

NCT00000228

COMPLETED Phase 2

Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1

NCT00000245

COMPLETED Phase 2

Flupenthixol Decanoate in Methamphetamine Smoking - 1

NCT00000241

COMPLETED Phase 2

Alternate-Day Buprenorphine Administration. Phase IV - 5

NCT00000223

COMPLETED Phase 2

Alternate Day Buprenorphine Administration, Phase X - 15

NCT00000233

COMPLETED Phase 1

Alternate-Day Buprenorphine. Phase V - 6

NCT00000224

COMPLETED Phase 2

Alternate-Day Buprenorphine Administration. Phase VI - 7

NCT00000225

COMPLETED Phase 2

Buprenorphine Dosing Interval - 5

NCT00000209

COMPLETED

The Genetic Basis for Vulnerability to Substance Abuse

NCT00247819

COMPLETED Phase 1

Alternate-Day Buprenorphine Administration. Phase II - 4

NCT00000222

COMPLETED Phase 2

Buprenorphine Maintenance for Opiate Dependence - 6

NCT00000357

COMPLETED Phase 1

Alternate-Day Buprenorphine Administration. Phase I - 3

NCT00000221

COMPLETED Phase 2

Methadone/Buprenorphine Cross-Over Study - 4

NCT00000208

COMPLETED Phase 2

Buprenorphine Detoxification With Two Types of Treatment. BBD IV - 13

NCT00000231

COMPLETED Phase 1

Gradual Vs. Rapid Buprenorphine Detoxification - 2

NCT00000220

COMPLETED Phase 2

Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5

NCT00000356

COMPLETED Phase 2

Treatment Efficacy for Drug Abuse and AIDS Prevention - 1

NCT00000210

COMPLETED Phase 2

Treatment Efficacy for Drug Abuse and AIDS Prevention - 2

NCT00000211

COMPLETED Phase 2

Propranolol for Treatment of Cocaine Addiction - 2

NCT00000197

COMPLETED Phase 2

Pharmacological Modulation of Cocaine Effects - 1

NCT00000201

COMPLETED Phase 2

Risperidone Treatment in Dually-Diagnosed Individuals - 2

NCT00000267

COMPLETED Phase 2

Buprenorphine Pharmacology Related to Addiction Treatment - 18

NCT00000236

COMPLETED Phase 1

Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7

NCT00000358

COMPLETED Phase 3

Study Comparing Liquid and Tablet Buprenorphine Formulations - 5

NCT00000302

COMPLETED Phase 2

Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1

NCT00218140

COMPLETED Phase 2

Buprenorphine Pharmacology Related to Addiction Treatment - 21

NCT00000239

COMPLETED Phase 1

Psychostimulant Abuse - Novel Treatment Approaches - 1

NCT00000325

COMPLETED Phase 2

Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9

NCT00000344

COMPLETED Phase 2

IV Cocaine Abuse: A Laboratory Model - 4

NCT00000215

COMPLETED Phase 4

Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9

NCT00015275

COMPLETED Phase 4

Pharmacotherapy and Intensive Treatment - 2

NCT00000218

COMPLETED Phase 2

Alternate Day Buprenorphine Administration, Phase XII - 17

NCT00000235

COMPLETED Phase 1

Alterations in Serotonergic Functions in Cocaine Addicts - 1

NCT00000312

TERMINATED Phase 1

Early Tobacco Abstinence - 5

NCT00224965

TERMINATED Phase 1

Predictive Values of Serotonergic Alterations for Outcome - 2

NCT00000313

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What the Pipeline for National Institute on Drug Abuse (NIDA) Shows

According to the ClinicalTrials.gov registry, National Institute on Drug Abuse (NIDA) is linked to 335 US clinical trials across every stage of research activity. Of those, 14 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 292 are already marked complete, representing roughly 87% of the total.

The phase mix for National Institute on Drug Abuse (NIDA) reports 30 late-stage studies (Phase 3 and Phase 4 combined) and 202 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute on Drug Abuse (NIDA) is Cocaine-Related Disorders with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.