National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials 155 currently recruiting 1642 completed

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Trial Pipeline

2,006 total, page 31 of 41

COMPLETED Phase 1

Safety of and Immune Response to an HIV-1 Vaccine Boost (VRC-HIVADV014-00-VP) in HIV Uninfected Adults Who Participated in HVTN 052

NCT00091416

COMPLETED NA

Influence of Probenecid and Quinine on the Pharmacokinetics of Azidothymidine

NCT00000706

COMPLETED Phase 3

A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients

NCT00001038

COMPLETED Phase 1

Safety and Acceptability of the Anti-Microbe Vaginal Gel, PMPA Gel

NCT00028132

COMPLETED Phase 2

A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients

NCT00001084

COMPLETED Phase 1

Use of a Varicella-Zoster Virus (VZV) Vaccine to Prevent Shingles in HIV-Infected Children Who Have Already Had Chickenpox

NCT00001125

COMPLETED Phase 1

A Study to Test the Safety of Recombinant Interleukin-2 (rIL-2) in HIV-Infected Children

NCT00000849

COMPLETED Phase 3

An Evaluation of IV Gamma Globulin As a Method to Improve Kidney Transplant Survival in Patients With End-Stage Renal Disease Who Are Highly Sensitized to Transplant Antigens

NCT00000935

COMPLETED NA

A Pilot Study of Allogeneic Lymphocyte Transfer in HIV Infection

NCT00000852

COMPLETED

A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients

NCT00000907

COMPLETED

A Study of HIV Levels During Pregnancy and After Childbirth

NCT00041964

COMPLETED Phase 1

A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children

NCT00000952

COMPLETED Phase 1

A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

NCT00000956

COMPLETED Phase 2

A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZT

NCT00000653

COMPLETED

Identifying Emergency Room Patients Who Have Recently Been Infected With HIV

NCT00001130

COMPLETED Phase 2

A Phase II Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Efficacy of Prednisone Therapy in HIV-Associated Nephropathy (HIVAN)

NCT00000819

COMPLETED Phase 2

The Effectiveness of Two Anti-HIV Treatments in HIV-Infected Patients

NCT00001057

COMPLETED Phase 1

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection

NCT00000984

COMPLETED Phase 1

Subcutaneously Administered Aldesleukin ( Interleukin-2; IL-2 ) Therapy in HIV-Infected Patients

NCT00000821

COMPLETED

Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048

NCT00000933

COMPLETED Phase 2

A Study of DAPD Alone Versus DAPD Plus MMF for Treatment of HIV Infection

NCT00038272

COMPLETED NA

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

NCT00013871

COMPLETED Phase 1

Interleukin-2 Plus Anti-HIV Therapy in HIV-Infected Children With Weakened Immune Systems

NCT00006066

COMPLETED Phase 2

Safety and Immune Response Study of the Vaccine ALVAC vCP1452 Alone or in Combination With AIDSVAX B/B

NCT00007332

COMPLETED Phase 1

An Investigational Combination Vaccine Given to People Who Are Not Infected With HIV

NCT00027365

COMPLETED

A Study of Patients With AIDS Syndrome

NCT00001120

COMPLETED Phase 1

A Phase I Safety, Efficacy, and Pharmacokinetic Study of 2',3'-Dideoxyinosine (ddI) Administered Twice Daily to Patients With AIDS or AIDS Related Complex

NCT00000710

COMPLETED Phase 2

A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure

NCT00000691

COMPLETED Phase 2

A Study of Tumor Necrosis Factor and Human Interferon-gamma in Patients With AIDS Related Complex

NCT00001004

COMPLETED Phase 2

A Phase II Efficacy Study Comparing 2',3'-Dideoxyinosine (ddI) (BMY-40900) and Zidovudine Therapy of Patients With HIV Infection Who Have Been on Long Term Zidovudine Treatment

NCT00000671

COMPLETED NA

A Study to Evaluate the Long-Term Effectiveness of Three Anti-HIV Drug Regimens in HIV Infected Patients Who Have Never Been Exposed to Highly Active Antiretroviral Therapy (HAART)

NCT00000922

COMPLETED Phase 1

The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection

NCT00001036

COMPLETED Phase 3

Study and Treatment of Post Lyme Disease (STOP-LD)

NCT00000937

COMPLETED Phase 2

Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease

NCT00001045

COMPLETED Phase 3

A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.

NCT00001100

COMPLETED Phase 1

Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative Adults

NCT00000877

COMPLETED NA

The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients

NCT00001023

COMPLETED NA

The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS

NCT00000717

COMPLETED Phase 2

A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection

NCT00000789

COMPLETED Phase 1

Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens

NCT00001091

COMPLETED Phase 2

Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma

NCT00000687

COMPLETED NA

Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy

NCT00000722

COMPLETED Phase 2

A Study of Disease Progression and Anti-HIV Treatments

NCT00001068

COMPLETED Phase 1

Safety of and Immune Response to an HIV Preventive Vaccine (HIV-1 Gag DNA Alone or With IL-15 DNA) Given With or Without 2 Different Booster Vaccinations in HIV Uninfected Adults

NCT00115960

COMPLETED Phase 2

Dexamethasone in Cryptococcal Meningitis

NCT00000776

COMPLETED Phase 2

Changing to Nonprotease Inhibitor Treatment to Improve Side Effects

NCT00021463

COMPLETED Phase 3

Effectiveness of AZT and Nevirapine in Preventing HIV Transmission From Ugandan Mothers to Their Newborns

NCT00006396

COMPLETED Phase 1

A Phase I Comparative Blinded Trial of Several HIV-1 Derived Immunogens in Infected Individuals With >= 500 CD4 Cells/mm3

NCT00000779

COMPLETED Phase 2

Comparison of ddI Versus Zidovudine in HIV-Infected Patients

NCT00000979

COMPLETED NA

A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis

NCT00000639

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows

According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.