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NCT00001068 · ClinicalTrials.gov registry record · Phase 2

A Study of Disease Progression and Anti-HIV Treatments

A Phase 2 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
210
Enrollment target
20
Study locations

NCT00001068: Completed Phase 2 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00001068 is a Phase 2 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 210 participants, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (53% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001068, a Phase 2 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
210 participants
Enrollment target
20
Study locations

Study Summary

To determine the influence of virus load, CD4 count, biologic phenotype, and presence of symptomatic disease on the response of HIV-infected patients to a new therapeutic regimen. PER AMENDMENT 8/27/96: To extend the availability of currently assigned ACTG 303 treatment for 6 months.

Conditions Studied

Interventions

  • DRUG Lamivudine

Study Locations (20)

California

  • USC CRS - Los Angeles
  • UCLA CARE Center CRS - Los Angeles
  • Stanford CRS - Palo Alto
  • Ucsd, Avrc Crs - San Diego
  • Ucsf Aids Crs - San Francisco
  • Santa Clara Valley Med. Ctr. - San Jose
  • San Mateo County AIDS Program - Stanford
  • Harbor-UCLA Med. Ctr. CRS - Torrance

Illinois

  • Northwestern University CRS - Chicago
  • Cook County Hosp. CORE Ctr. - Chicago
  • Rush Univ. Med. Ctr. ACTG CRS - Chicago

Massachusetts

  • Massachusetts General Hospital ACTG CRS - Boston
  • Bmc Actg Crs - Boston

Alabama

  • Alabama Therapeutics CRS - Birmingham

Colorado

  • University of Colorado Hospital CRS - Aurora

Florida

  • Univ. of Miami AIDS CRS - Miami

Georgia

  • Emory Univ. Hemophilia Program Office - Atlanta

Indiana

  • Indiana Univ. School of Medicine, Infectious Disease Research Clinic - Indianapolis

Trial Details

FieldValue
Enrollment Target 210 participants
Est. Completion 1998-10
Phase Phase 2

What the finished NCT00001068 record still lists

NCT00001068 is an interventional study that assigns participants to a tested intervention. The registered 210 participants enrollment target is mid-sized for trials with a published cap, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (53% lower).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Lamivudine is the first listed.

NCT00001068 names 20 study sites across 10 states, led by California, Illinois, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00001068 about?

NCT00001068 is a clinical study titled "A Study of Disease Progression and Anti-HIV Treatments". To determine the influence of virus load, CD4 count, biologic phenotype, and presence of symptomatic disease on the response of HIV-infected patients to a new therapeutic regimen. PER AMENDMENT 8/27/96: To extend the availability of currently assigned ACTG 303 treatment for 6 months.

What is the current status of trial NCT00001068?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 210 participants. Estimated completion is 1998-10.

What conditions does trial NCT00001068 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT00001068?

The interventions under investigation include: Lamivudine (DRUG).

Who is sponsoring clinical trial NCT00001068?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001068 being conducted?

This trial has 20 study locations across Alabama, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001068's enrollment target sits among peer trials

210 164th of 542 higher than 377 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

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Source: ClinicalTrials.gov NCT00001068, the US trial registry maintained by the National Library of Medicine. NCT00001068 (mid enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.