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NCT00000984 · ClinicalTrials.gov registry record · Phase 1
A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection
A Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 6
- Study locations
NCT00000984 is a Phase 1 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 40 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (91% lower). The trial reports 6 study locations across 4 states.
The verdict
NCT00000984, a Phase 1 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 6
- Study locations
Study Summary
AMENDED: As of 10/19/90 only Children 0 to 3 months are being enrolled. Original design: To determine whether the experimental drug recombinant CD4 (rCD4), which is produced through genetic engineering technology, is safe and well-tolerated in children infected with or at risk for HIV infection. rCD4 may be an effective treatment for HIV infection, based on its ability to block infection of human cells by HIV in laboratory tests. However, the activity of rCD4 still needs to be confirmed in clinical trials. It is hoped that these tests will show that rCD4 is both safe and effective in treating children who are infected with or who are at risk for infection with HIV.
Conditions Studied
Interventions
- DRUG CD4 Antigens
Study Locations (6)
California
- Northern California Pediatric AIDS Treatment Ctr / UCSF - San Francisco
- Stanford Univ School of Medicine / Pediatrics - Stanford
Illinois
- Chicago Children's Memorial Hosp - Chicago
- Children's Memorial Med Ctr - Chicago
New Jersey
- Children's Hosp of New Jersey / UMDNJ - New Jersey Med Schl - Newark
North Carolina
- Duke Univ Med Ctr - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00000984
The ClinicalTrials.gov registry entry for NCT00000984 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (91% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which CD4 Antigens is the first listed.
NCT00000984 reports 6 study locations spanning 4 distinct geographic areas - top geographies include California, Illinois, New Jersey.
Frequently Asked Questions
What is clinical trial NCT00000984 about?
NCT00000984 is a clinical study titled "A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection". AMENDED: As of 10/19/90 only Children 0 to 3 months are being enrolled. Original design: To determine whether the experimental drug recombinant CD4 (rCD4), which is produced through genetic engineering technology, is safe and well-tolerated in children infected with or at risk for HIV infection. rC...
What is the current status of trial NCT00000984?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants.
What conditions does trial NCT00000984 study?
This clinical trial studies the following conditions: HIV Infections.
What interventions are being tested in trial NCT00000984?
The interventions under investigation include: CD4 Antigens (DRUG).
Who is sponsoring clinical trial NCT00000984?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00000984 being conducted?
This trial has 6 study locations across California, Illinois, New Jersey, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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