National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 14 of 41

COMPLETED Phase 1

Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults

NCT01783977

COMPLETED

Malaria Transmission Studies in Mali

NCT01829737

COMPLETED Phase 1

Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and Children

NCT01504841

COMPLETED Phase 1

Idebenone for Primary Progressive Multiple Sclerosis

NCT01854359

COMPLETED Phase 1

Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)

NCT04870138

TERMINATED Phase 1

Sirolimus for Eosinophil-Associated Gastrointestinal Disorders

NCT01814059

COMPLETED Phase 1

Intranasal AD4-H5-VTN as an Adenovirus Vaccine

NCT01806909

COMPLETED Phase 1

LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine

NCT01751048

COMPLETED

Validation of Gene Expression Markers of Renal Allograft Functional Decline

NCT01782586

TERMINATED Phase 2

Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney Transplantation

NCT01790594

TERMINATED Phase 1

Bone Marrow Stromal Cells for Inflammatory Bowel Diseases

NCT01851343

COMPLETED Phase 1

Safety and Immunogenicity of Two Live, Attenuated Oral Shigella Sonnei Vaccines: WRSs2 and WRSs3

NCT01336699

COMPLETED

Effect of Filarial Infection on Immune Responses in Latent Tuberculosis

NCT01547884

COMPLETED Phase 1

Sildenafil for PNTM Infection

NCT01853540

COMPLETED Phase 2

Safety and Immunogenicity of a Monovalent Inactivated Influenza H3N2 Variant (H3N2v) Vaccine in Adult and Elderly Populations

NCT01746082

COMPLETED Phase 1

Evaluating the Safety and Immune Response to Two Doses of a Dengue Virus Vaccine Administered 12 Months Apart

NCT01782300

COMPLETED Phase 2

Combination Therapy for Chronic Hepatitis C Infection

NCT01805882

COMPLETED Phase 1

Testing the AVI-7100 Flu Drug in Healthy Volunteers

NCT01747148

COMPLETED

Volunteer Screening for Vaccine and Antivirals Clinical Trials

NCT01593709

COMPLETED

Studying Cell Immune Responses to a Live Flu Vaccine in Healthy Adults

NCT01730144

COMPLETED Phase 4

CMV Antiviral Prevention Strategies in D+R-Liver Transplants ("CAPSIL")

NCT01552369

COMPLETED Phase 4

Tdap Vaccine in Post-Partum Women

NCT01711645

COMPLETED Phase 2

A Phase IIb, Open-Label, Dose Ranging Study of 13-Valent Pneumococcal Conjugate Vaccine in Adults 55 Through 74 Years of Age Previously Vaccinated With 23-Valent Pneumococcal Polysaccharide Vaccine

NCT01654263

COMPLETED NA

Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Study

NCT01737710

COMPLETED NA

Assessment of Pre-Exposure Prophylaxis (PrEP) Administered at Sexually Transmitted Disease (STD) Clinics

NCT01632995

COMPLETED Phase 1

Study of Immune Responses in Healthy Adults Receiving Live Influenza Virus Vaccines

NCT01674205

COMPLETED Phase 1

Effect of PA-824 and of PA-824 Plus Moxifloxacin on the QTc Interval in Healthy Volunteers

NCT01674218

COMPLETED

Clinical Outcomes of People Who Acquired HIV in Early Life

NCT01656564

COMPLETED Phase 2

Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients

NCT01638559

COMPLETED Phase 1

Seasonal Influenza HA DNA With Trivalent Inactivated Vaccine (TIV) Administered ID or IM in Healthy Adults 18-70 Years

NCT01676402

COMPLETED Phase 1

Study of the Safety and Local Tolerability of Intranasal Gel Formulations of XF-73

NCT01592214

COMPLETED

Genomics of Kidney Transplantation

NCT01714440

COMPLETED

Discovery and Validation of Proteogenomic Biomarker Panels in Liver Transplant Recipients

NCT01672164

COMPLETED Phase 4

Assessment of the Immunogenicity and Safety of a Dose-Sparing BioThrax® AVA Schedule

NCT01641991

TERMINATED Phase 2

Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome

NCT01552681

COMPLETED Phase 1

Evaluating the Pharmacokinetics of High-Dose Rifapentine When Given as a Single Dose or in Divided Doses to Healthy Adults

NCT01574638

COMPLETED Phase 2

Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women

NCT01505114

COMPLETED Phase 1

Seasonal Influenza DNA Vaccine & Seasonal Influenza Trivalent Inactivated Vaccine (TIV) in Children & Adolescents

NCT01609998

COMPLETED

Gene Expression in HIV and Tuberculosis Co-infection

NCT01611402

COMPLETED Phase 1

H5N1 Vaccination With and Without AS03: Systems Biology Analysis

NCT01573312

COMPLETED Phase 3

Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)

NCT01404312

COMPLETED Phase 1

Phase I Trial of a Single Dose of CRS3123

NCT01551004

COMPLETED Phase 2

The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children"

NCT01595529

COMPLETED Phase 1

Evaluating the Safety and Drug Interaction of PA-824, an Investigational Tuberculosis Medication, Together With Efavirenz, Ritonavir-Boosted Lopinavir, or Rifampin

NCT01571414

COMPLETED Phase 1

Evaluating the Safety of and Immune Response to HIV-MAG DNA Vaccine With or Without Plasmid IL-12 Adjuvant Delivered Intramuscularly Via Electroporation Followed by VSV-gag HIV Vaccine Boost in Healthy, HIV-Uninfected Adults

NCT01578889

COMPLETED Phase 1

Sanaria™ PfSPZ Challenge Vaccine

NCT01546389

COMPLETED Phase 1

Evaluating the Safety and Immune Response of a Prime-Boost HIV Vaccine Regimen in Healthy, HIV-Uninfected, Vaccinia-Naive Adults

NCT01571960

COMPLETED

Perceived Barriers to Patient Adherence After Pediatric Solid Organ Transplantation

NCT01370746

COMPLETED Phase 3

Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV Infection

NCT01482767

COMPLETED Phase 1

Immune Responses to H5N1 Vaccine With and Without AS03 Adjuvant

NCT01578317

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.