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NCT01783977 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
143
Enrollment target

NCT01783977: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT01783977 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 143 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (138% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01783977, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
143 participants
Enrollment target

Study Summary

NOTE: This study has stopped enrolling new participants, and all study vaccinations for currently enrolled participants have been stopped. Currently, there are no vaccines approved for the prevention of HIV infection, but there are many clinical trials taking place that are studying experimental HIV vaccines. The purpose of this study is to evaluate the safety and tolerability of three different HIV vaccine schedules in healthy, HIV-uninfected adults.

Interventions

  • BIOLOGICAL DNA-HIV-PT123 vaccine
  • BIOLOGICAL NYVAC-HIV-PT1 vaccine
  • BIOLOGICAL NYVAC-HIV-PT4 vaccine
  • BIOLOGICAL Placebo for DNA-HIV-PT123 vaccine
  • BIOLOGICAL Placebo for NYVAC-HIV-PT1 vaccine

Trial Details

FieldValue
Enrollment Target 143 participants
Start Date 2013-04
Est. Completion 2018-10-24
Phase Phase 1

What the finished NCT01783977 record still lists

NCT01783977 is an interventional study that assigns participants to a tested intervention. The registered 143 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (138% higher).

The record links to 0 conditions, and to 5 interventions - of which DNA-HIV-PT123 vaccine is the first listed.

NCT01783977 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01783977 about?

NCT01783977 is a clinical study titled "Evaluating the Safety and Immune Response to Three HIV Vaccine Schedules in Healthy, HIV-Uninfected Adults". NOTE: This study has stopped enrolling new participants, and all study vaccinations for currently enrolled participants have been stopped. Currently, there are no vaccines approved for the prevention of HIV infection, but there are many clinical trials taking place that are studying experimental HI...

What is the current status of trial NCT01783977?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 143 participants. The study started on 2013-04. Estimated completion is 2018-10-24.

What interventions are being tested in trial NCT01783977?

The interventions under investigation include: DNA-HIV-PT123 vaccine (BIOLOGICAL), NYVAC-HIV-PT1 vaccine (BIOLOGICAL), NYVAC-HIV-PT4 vaccine (BIOLOGICAL), Placebo for DNA-HIV-PT123 vaccine (BIOLOGICAL), Placebo for NYVAC-HIV-PT1 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01783977?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01783977's enrollment target sits among peer trials

143 401st of 2000 higher than 1,600 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01783977, the US trial registry maintained by the National Library of Medicine. NCT01783977 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.