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NCT01571960 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Safety and Immune Response of a Prime-Boost HIV Vaccine Regimen in Healthy, HIV-Uninfected, Vaccinia-Naive Adults

A Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
48
Enrollment target
4
Study locations

NCT01571960 is a Phase 1 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 48 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (89% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT01571960, a Phase 1 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
48 participants
Enrollment target
4
Study locations

Study Summary

This study will test the safety and immune responses of a prime-boost regimen of two HIV vaccines- a DNA vaccine followed by a modified vaccinia Ankara (MVA) vaccine- in healthy, HIV-uninfected, vaccinia-naive adults.

Conditions Studied

Interventions

  • BIOLOGICAL GEO-D03 DNA vaccine
  • BIOLOGICAL MVA/HIV62B (MVA62B) vaccine
  • BIOLOGICAL Placebo for GEO-D03 DNA
  • BIOLOGICAL Placebo for MVA62B:

Study Locations (4)

Alabama

  • Alabama CRS - Birmingham

California

  • Bridge HIV CRS - San Francisco

Massachusetts

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) - Boston

New York

  • University of Rochester Vaccines to Prevent HIV Infection CRS - Rochester

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2012-04
Est. Completion 2016-01
Phase Phase 1

What the Registry Record Tells You About NCT01571960

The ClinicalTrials.gov registry entry for NCT01571960 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (89% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 4 interventions - of which GEO-D03 DNA vaccine is the first listed.

NCT01571960 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Alabama, California, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01571960 about?

NCT01571960 is a clinical study titled "Evaluating the Safety and Immune Response of a Prime-Boost HIV Vaccine Regimen in Healthy, HIV-Uninfected, Vaccinia-Naive Adults". This study will test the safety and immune responses of a prime-boost regimen of two HIV vaccines- a DNA vaccine followed by a modified vaccinia Ankara (MVA) vaccine- in healthy, HIV-uninfected, vaccinia-naive adults.

What is the current status of trial NCT01571960?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2012-04. Estimated completion is 2016-01.

What conditions does trial NCT01571960 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT01571960?

The interventions under investigation include: GEO-D03 DNA vaccine (BIOLOGICAL), MVA/HIV62B (MVA62B) vaccine (BIOLOGICAL), Placebo for GEO-D03 DNA (BIOLOGICAL), Placebo for MVA62B: (BIOLOGICAL).

Who is sponsoring clinical trial NCT01571960?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01571960 being conducted?

This trial has 4 study locations across Alabama, California, Massachusetts, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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