National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 13 of 41

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Live H7N9 Influenza Virus Vaccine Followed by an Inactivated H7N9 Influenza Virus Vaccine, Given at Varying Intervals

NCT02151344

COMPLETED Phase 2

Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants

NCT01827358

COMPLETED Phase 1

Rituximab for Anti-cytokine Autoantibody-Associated Diseases

NCT01842386

COMPLETED

Zoonotic Influenza Infections of Swine Origin at Ohio Agricultural Fairs

NCT02124096

COMPLETED Phase 2

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

NCT02081638

COMPLETED Phase 1

Auranofin PK Following Oral Dose Administration

NCT02089048

COMPLETED

ADRN Barrier/Immunoprofiling Exploratory Pilot Study

NCT02115399

COMPLETED

Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease

NCT02233036

COMPLETED Phase 2

Efficacy of Ustekinumab Followed by Abatacept for the Treatment of Psoriasis Vulgaris

NCT01999868

COMPLETED Phase 1

Safety of Sublingual dmLT for ETEC

NCT02052934

TERMINATED Early Phase 1

Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor

NCT02069080

COMPLETED

Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy

NCT01976715

COMPLETED

Patients Treated for Wiskott-Aldrich Syndrome (WAS) Since 1990

NCT02064933

COMPLETED Phase 1

Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of Age

NCT02186626

COMPLETED Phase 2

Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications

NCT01949116

COMPLETED Phase 1

Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at Risk of Acquiring HIV-1 Infection

NCT01780831

TERMINATED Phase 2

BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance

NCT02029638

TERMINATED

T and B Cell Responses in Autoimmune Diseases

NCT01947036

COMPLETED Phase 1

Study of Controlled Human Malaria Infections to Evaluate Protection After Intravenous or Intramuscular Administration of PfSPZ Vaccine in Malaria-Naive Adults

NCT02015091

COMPLETED Phase 1

Anti-Influenza Hyperimmune Intravenous Immunoglobulin Pilot Study (INSIGHT 005: Flu-IVIG Pilot)

NCT02008578

COMPLETED Phase 1

The Pharmacokinetics of Extended Duration High-dose Cefixime for the Decreased Susceptibility of Neisseria Gonorrhoeae: A Phase I Pilot Study

NCT01949363

TERMINATED Phase 2

Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)

NCT01946880

COMPLETED Phase 1

Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB060-00-AB (VRC01), Administered Intravenously or Subcutaneously to Healthy Adults

NCT01993706

COMPLETED Phase 1

Study of Safety and Immunogenicity of HIV Vaccines in Healthy Volunteers

NCT01989533

COMPLETED Phase 1

Evaluating the Safety and Effectiveness of a Dengue Virus Vaccine in Healthy Adults

NCT02021968

TERMINATED Phase 2

Trichuris Suis Ova Treatment in Left-sided Ulcerative Colitis

NCT01953354

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children

NCT01968083

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children

NCT01852266

COMPLETED

A Retrospective Multicenter Study to Determine 5-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-01 Study

NCT01974999

COMPLETED Phase 1

Safety and Immunogenicity of a Live Attenuated H7N9 Influenza Virus Vaccine in Healthy Adults

NCT01995695

COMPLETED Phase 1

Study of the Safety of a Particular Herpes Vaccine in Adults With or Without Herpes Infection

NCT01915212

COMPLETED Phase 1

Evaluation of Anti-Hemagglutinin (Anti-HA) Antibodies as Protection From the Flu in Healthy People

NCT01971255

COMPLETED Phase 2

Peanut Epicutaneous Phase II Immunotherapy Clinical Trial

NCT01904604

COMPLETED Phase 2

H7N9 Mix and Match With MF59 in Healthy Adults

NCT01938742

COMPLETED Phase 2

H7N9 Mix and Match With AS03 and MF59 in Healthy Adults

NCT01942265

COMPLETED Phase 1

VRC 601: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC HIVMAB060-00-AB (VRC01), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to HIV-Infected...

NCT01950325

COMPLETED Phase 2

Peanut Oral Immunotherapy in Children

NCT01867671

TERMINATED Phase 1

Aerosolized and Intravenous Colistin in Healthy Adults

NCT01863719

COMPLETED

Study of the Complications Associated With Certain Stem Cell Transplants

NCT01919099

TERMINATED

Study of Antibiotic-induced Vaginal Yeast Infections in Healthy Women

NCT01915251

COMPLETED Phase 2

Systems Biology of Influenza A (H5N1) Virus Monovalent Vaccine With and Without Adjuvant System 03 (AS03)

NCT01910519

TERMINATED Phase 2

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

NCT01856257

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in Infants and Children

NCT01893554

COMPLETED Phase 1

Evaluating the Safety and Immune Response to a Dengue Virus Vaccine in Healthy Adults

NCT01931176

COMPLETED Phase 2

Study of A Combination Pill With GS-7977 and GS-5885 for Hepatitis C in People With HIV

NCT01878799

COMPLETED Phase 2

Phase II Trial to Assess Safety and Immunogenicity of IMVAMUNE®

NCT01827371

TERMINATED Phase 2

Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation

NCT01769443

TERMINATED Phase 2

Vitamin D3 Treatment in Pediatric Systemic Lupus Erythematosus

NCT01709474

COMPLETED Phase 1

Therapeutic Vaccine for HIV

NCT01859325

COMPLETED Phase 1

Evaluation of Intravaginal Gel and Ovule Formulations of TOL-463

NCT01812889

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.