National Human Genome Research Institute (NHGRI)
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, National Human Genome Research Institute (NHGRI) sits in the top decile of US sponsors by registered trial count (#161 of 15,742 sponsors by registered trial count).
National Human Genome Research Institute (NHGRI): 185 sponsored US clinical trials, 30 recruiting.
National Human Genome Research Institute (NHGRI) sponsors 185 registered US clinical trials on ClinicalTrials.gov, 30 of them currently recruiting, and 143 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Proteus Syndrome, with 3 trials.
Top-decile sponsor footprint
National Human Genome Research Institute (NHGRI) ranks in the top decile of sponsors by registered trial count (#161 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
143 of 152 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (94.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
185 total, page 4 of 4
Family Myopia Study
NCT00341549
Genetic Analysis of Fraser Syndrome and Fryns Syndrome
NCT00032877
Exploratory Data Analysis for Disease Pedigrees and Cancer Genetics
NCT00339508
Analysis of Prostate Cancer Short-Term Cultures Using Molecular Cytogenetic Methods
NCT00022919
Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency
NCT00018018
Molecular Analysis of Microphthalmia/Anophthalmia
NCT00011843
Genetic Analysis of Oculocerebrorenal Syndrome of Lowe
NCT00359515
Genetic Analysis of Familial Brain Aneurysms
NCT00011856
Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID
NCT00006335
Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion Bodies
NCT00006176
Risk Evaluation and Education for Alzheimer's Disease
NCT00571025
Gene Therapy and Ganciclovir in Treating Patients With Stage IV Melanoma
NCT00005057
Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly
NCT00005016
Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)
NCT00046059
Study of the Results of Education and Counseling for Persons Undergoing Genetic Testing for Hereditary Nonpolyposis Colon Cancer
NCT00004210
Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population
NCT00341068
Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome
NCT00001966
Genetic Analysis of Left-Right Axis Formations
NCT00341133
Microarray Analysis for Human Genetic Disease
NCT00001898
Lung Disease Associated With Rheumatoid Arthritis
NCT00001876
Genetic Analysis of Familial Melanoma
NCT00339404
Study of Skeletal Disorders and Short Stature
NCT00001754
Gene Analysis of Parkinson's Disease
NCT00001643
Positional Cloning of the Gene(s) Responsible for Alagille Syndrome
NCT00001642
Study of Heritable Connective Tissue Disorders
NCT00001641
Genetic Analysis of Parkinson's Disease
NCT00001640
Evaluation of Patients With Unresolved Chromosome Abnormalities
NCT00001639
Issues Surrounding Prenatal Genetic Testing for Achondroplasia
NCT00001536
Twins Study of Gene Therapy for HIV Infection
NCT00001535
Outcomes of Education and Counseling for BRCA1 Testing
NCT00001468
Genetic Analysis of Hereditary Prostate Cancer
NCT00001469
Study of Clinical and Molecular Manifestations of Genetic Disorders
NCT00001466
Phenotype and Etiology of Pallister-Hall Syndrome
NCT00001404
Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study
NCT00001255
Personalized Medicine Decision-Making in a Virtual Clinical Setting
NCT02108041
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 7 |
Therapeutic Areas
What is open in the National Human Genome Research Institute (NHGRI) pipeline
30 recruiting of 185 indexed (16% open); 143 completed (77%).
Phase mix: 0 late (III/IV) vs 18 early (I/II) (early-phase heavy).
Top condition: Proteus Syndrome (3 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
National Human Genome Research Institute (NHGRI): open-pipeline peers nationwide
Peers matched on 185 registered trials and 16% open enrollment, not the therapeutic-area sidebar.
National Human Genome Research Institute (NHGRI) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 185 trials (± recruiting share)
- Boston University · 185 trials · 12% recruiting
- Children's Mercy Hospital Kansas City · 184 trials · 11% recruiting
- Arizona State University · 187 trials · 15% recruiting
- Johns Hopkins Bloomberg School of Public Health · 187 trials · 14% recruiting
Sponsors near 16% open enrollment (± trial volume)
- BioMarin Pharmaceutical · 16% recruiting · 80 trials
- Atlantic Health System · 16% recruiting · 43 trials
- Drexel University · 16% recruiting · 92 trials
- Case Western Reserve University · 16% recruiting · 141 trials
Related
What to do with this National Human Genome Research Institute (NHGRI) page
185 registered trials is a research-attention snapshot, not an endorsement of National Human Genome Research Institute (NHGRI) or any single study.
- 30 of National Human Genome Research Institute (NHGRI)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Proteus Syndrome is the condition National Human Genome Research Institute (NHGRI) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Proteus Syndrome trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Human Genome Research Institute (NHGRI) pipeline card: 185 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.