National Human Genome Research Institute (NHGRI)

185 total trials 30 currently recruiting 143 completed

National Human Genome Research Institute (NHGRI) sponsors 185 registered US clinical trials on ClinicalTrials.gov, 30 of them currently recruiting, and 143 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Proteus Syndrome, with 3 trials.

Trial Pipeline

185 total, page 4 of 4

COMPLETED

Family Myopia Study

NCT00341549

COMPLETED

Genetic Analysis of Fraser Syndrome and Fryns Syndrome

NCT00032877

COMPLETED

Exploratory Data Analysis for Disease Pedigrees and Cancer Genetics

NCT00339508

COMPLETED

Analysis of Prostate Cancer Short-Term Cultures Using Molecular Cytogenetic Methods

NCT00022919

COMPLETED Phase 1

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

NCT00018018

COMPLETED

Molecular Analysis of Microphthalmia/Anophthalmia

NCT00011843

COMPLETED

Genetic Analysis of Oculocerebrorenal Syndrome of Lowe

NCT00359515

COMPLETED

Genetic Analysis of Familial Brain Aneurysms

NCT00011856

COMPLETED

Influences on Female Adolescents' Decisions Regarding Testing for Carrier Status of XSCID

NCT00006335

COMPLETED

Clinical and Genetic Studies of Familial Presenile Dementia With Neuronal Inclusion Bodies

NCT00006176

COMPLETED NA

Risk Evaluation and Education for Alzheimer's Disease

NCT00571025

COMPLETED Phase 1

Gene Therapy and Ganciclovir in Treating Patients With Stage IV Melanoma

NCT00005057

COMPLETED

Study of the Experiences and Needs of Parents Continuing a Pregnancy Following a Prenatal Diagnosis of Holopresencephaly

NCT00005016

COMPLETED

Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)

NCT00046059

COMPLETED NA

Study of the Results of Education and Counseling for Persons Undergoing Genetic Testing for Hereditary Nonpolyposis Colon Cancer

NCT00004210

TERMINATED

Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population

NCT00341068

COMPLETED Phase 2

Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome

NCT00001966

COMPLETED

Genetic Analysis of Left-Right Axis Formations

NCT00341133

COMPLETED

Microarray Analysis for Human Genetic Disease

NCT00001898

COMPLETED

Lung Disease Associated With Rheumatoid Arthritis

NCT00001876

COMPLETED

Genetic Analysis of Familial Melanoma

NCT00339404

COMPLETED

Study of Skeletal Disorders and Short Stature

NCT00001754

COMPLETED

Gene Analysis of Parkinson's Disease

NCT00001643

COMPLETED

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

NCT00001642

COMPLETED

Study of Heritable Connective Tissue Disorders

NCT00001641

COMPLETED

Genetic Analysis of Parkinson's Disease

NCT00001640

COMPLETED

Evaluation of Patients With Unresolved Chromosome Abnormalities

NCT00001639

COMPLETED

Issues Surrounding Prenatal Genetic Testing for Achondroplasia

NCT00001536

COMPLETED Phase 1

Twins Study of Gene Therapy for HIV Infection

NCT00001535

COMPLETED

Outcomes of Education and Counseling for BRCA1 Testing

NCT00001468

COMPLETED

Genetic Analysis of Hereditary Prostate Cancer

NCT00001469

COMPLETED

Study of Clinical and Molecular Manifestations of Genetic Disorders

NCT00001466

COMPLETED

Phenotype and Etiology of Pallister-Hall Syndrome

NCT00001404

COMPLETED

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

NCT00001255

COMPLETED

Personalized Medicine Decision-Making in a Virtual Clinical Setting

NCT02108041

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What the Pipeline for National Human Genome Research Institute (NHGRI) Shows

According to the ClinicalTrials.gov registry, National Human Genome Research Institute (NHGRI) is linked to 185 US clinical trials across every stage of research activity. Of those, 30 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 143 are already marked complete, representing roughly 77% of the total.

The phase mix for National Human Genome Research Institute (NHGRI) reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Human Genome Research Institute (NHGRI) is Proteus Syndrome with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.