Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00113464 · ClinicalTrials.gov registry record

Developing Newborn Screening for Infants With Primary Immunodeficiency

A clinical trial, sponsored by National Human Genome Research Institute (NHGRI).

Completed
Registry status
100
Enrollment target

NCT00113464 is a clinical trial that has completed, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 100 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00113464 has completed, sponsored by National Human Genome Research Institute (NHGRI).

COMPLETED
Registry status
100 participants
Enrollment target

Study Summary

This study will explore screening for immunodeficiency diseases (diseases that cause problems in fighting infections). There is no method at present to screen all babies at birth for immunodeficiency. However, babies with low numbers of T-cells-an important type of immune system cell-may be found by studying T-cell products called TRECs (T-cell receptor excision circles). This study will: * Collect samples from children with several different immunodeficiencies to find out which disorders can be found by screening dried blood spots for TRECs. * Try to develop screening tests based on other kinds of material derived from dried blood spots. Children with primary immunodeficiency and low numbers of T cells who have not had a bone marrow transplant may be eligible for this study. Participating children donate up to 5 ml (1 teaspoon) of blood. The sample may be collected when the child is having other blood tests. The liquid blood is analyzed to determine the number of T cells, and the rest of the blood is used to make dried blood spots on filter paper. The blood spots are used to develop screening tests for immunodeficiency. The blood spots and data about the child's age, diagnosis, and current medicines will be kept coded by diagnosis and a code number instead of the child's name.

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2005-06-02
Est. Completion 2007-04-13

What the Registry Record Tells You About NCT00113464

The ClinicalTrials.gov registry entry for NCT00113464 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Human Genome Research Institute (NHGRI), which has 185 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00113464 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00113464 about?

NCT00113464 is a clinical study titled "Developing Newborn Screening for Infants With Primary Immunodeficiency". This study will explore screening for immunodeficiency diseases (diseases that cause problems in fighting infections). There is no method at present to screen all babies at birth for immunodeficiency. However, babies with low numbers of T-cells-an important type of immune system cell-may be found by...

What is the current status of trial NCT00113464?

This trial is currently completed. The enrollment target is 100 participants. The study started on 2005-06-02. Estimated completion is 2007-04-13.

Who is sponsoring clinical trial NCT00113464?

This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.