Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 44 of 57

COMPLETED NA

Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab

NCT01393821
COMPLETED NA

The Role That Peroral Endoscopic Myotomy (POEM) Could Play in the Treatment of Achalasia

NCT01584635
COMPLETED Phase 2

Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain

NCT01906944
COMPLETED

Betrnet Stem Cells and the Origins of Barrett's Esophagus Project 3 RF Ablation

NCT01568723
COMPLETED Phase 1

Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants

NCT01864057
COMPLETED Phase 2

LIPS-A: Lung Injury Prevention Study With Aspirin

NCT01504867
TERMINATED Phase 2

Intra-op Detection of Occult Ovarian Carcinoma Using a Folate-Alpha Receptor Specific Fluorescent Ligand

NCT01511055
COMPLETED

Early or Late Foley Removal After Thoracotomy

NCT01611519
COMPLETED

Novel Methodology to Measure Protein Accumulation

NCT01505621
COMPLETED Early Phase 1

Treatment of Muscle Cramps in Patients With Liver Cirrhosis

NCT01495403
COMPLETED NA

Effects of Calorie Restriction on Accumulation of Old, Modified Proteins in Abdominally Obese Adults

NCT01497106
COMPLETED

Self Efficacy, Walking Ability, Gait Speed and Physical Activity in People With Chronic Lung Disease

NCT01583595
COMPLETED NA

Effects of Aerobic and Resistance Training on Accumulation of Old, Modified Proteins in Young and Older Adults

NCT01477164
COMPLETED Phase 1

Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

NCT01503177
COMPLETED Phase 2

MEmbranous Nephropathy Trial Of Rituximab

NCT01180036
COMPLETED Phase 1

The Biomechanical Effects of Flaccid Paralysis Induced by Botulinum Toxin a After Damage Control Laparotomy

NCT01495962
TERMINATED NA

Superficial Cervical Plexus Block for Pacemaker Insertion

NCT01473667
COMPLETED Phase 4

Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia

NCT01471756
COMPLETED NA

Intensive Glycemic Management and Outcomes Following Liver Transplantation

NCT01432093
COMPLETED NA

Physiologic Effects of Sleep Restriction

NCT01433315
COMPLETED NA

Anthropometry in Gastroesophageal Reflux Disease and Esophageal Injury

NCT01570842
COMPLETED Phase 1

Pomalidomide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT01212952
COMPLETED NA

Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome

NCT01500902
COMPLETED NA

Aspiration for Pain Relief Following Ankle Fracture

NCT01484535
COMPLETED NA

Physical Activity Intervention in Preschool Children

NCT02524132
COMPLETED NA

Part vs Whole Task Mastery Training for Laparoscopic Hernia Repair

NCT01629485
COMPLETED

Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study

NCT01456871
COMPLETED NA

Leptin Biology in Adipose Tissue

NCT01800864
COMPLETED

Assessment of Cardiac Allograft Vasculopathy With Optical Coherence Tomography

NCT01527344
COMPLETED

Study of Exercise and Heart Function in Patients With Heart Failure and Pulmonary Vascular Disease

NCT01418248
COMPLETED

Early Detection of Pulmonary Arterial Hypertension Using Cardiac Magnetic Resonance Imaging

NCT01451255
COMPLETED NA

Cerebrospinal Fluid (CSF) Drainage Study

NCT01420978
TERMINATED NA

Polar Wand Carbon Dioxide Cryotherapy for Barrett's Esophagus

NCT01477177
COMPLETED NA

Effect of Self Regulation With Mindfulness Training on Body Mass Index and Cardiovascular Risk Markers in Obese Adults

NCT01375504
COMPLETED NA

Support Person Intervention to Promote a Smoking Helpline

NCT01331226
COMPLETED NA

Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA)

NCT01391182
COMPLETED Phase 3

A Trial of Magnesium Dependent Tinnitus

NCT01273883
COMPLETED NA

Silver-impregnated Suprapubic Catheters (SPC) in Urogynecology

NCT01359046
COMPLETED NA

A Comparison of Single Port and Four Port Laparoscopic Gallbladder Removal

NCT01489436
COMPLETED

Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device(VAD)Patients

NCT01415869
COMPLETED

Long-term Outcomes of Patients With Primary Amyloidosis After Stem Cell Transplantation

NCT01606280
COMPLETED

LMA Cuff Pressure and LMA-induced Complications

NCT01385969
COMPLETED Phase 2

Varenicline Treatment for Active Alcoholic Smokers

NCT01347112
COMPLETED

Assessment of Endothelial Function, Apolipoproteins and Adiponectin

NCT01300390
COMPLETED Phase 1

Pilot Study of Varenicline to Treat Opioid Dependence

NCT01436474
COMPLETED Phase 2

Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility

NCT01379183
COMPLETED Phase 2

Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction

NCT01286168
COMPLETED Phase 1

Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy

NCT01703143
COMPLETED NA

Ketamine Anesthesia in Electroconvulsive Therapy

NCT01367119
COMPLETED Phase 4

Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans

NCT01500317
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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

Therapeutic Areas

Healthy 36
Malignant Solid Neoplasm 35
Obesity 31
Breast Cancer 25
Breast Carcinoma 21
Hematopoietic and Lymphatic System Neoplasm 20
Hematopoietic and Lymphoid System Neoplasm 12
Heart Failure 11
Cancer 11
Prostate Carcinoma 9

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.