Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 43 of 57

COMPLETED Phase 1

Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT01606241

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Previously Treated Stage II-III HER2-Positive Breast Cancer

NCT01632332

COMPLETED Phase 2

Bridging Study of C11 Pittsburgh Compound B (PiB) and F18 Flutemetamol Brain Positron Emission Tomography (PET)

NCT01607476

COMPLETED NA

Continous Positive Airway Pressure (CPAP) Compliance Study

NCT01642160

COMPLETED NA

Sleep Restriction and Obesity

NCT01580761

COMPLETED NA

Mechanisms of Altered Ventilatory Control in Heart Failure

NCT02421341

COMPLETED NA

Evaluation of Half-Dose Molecular Breast Imaging With Wide Beam Reconstruction Processing

NCT01653964

COMPLETED NA

Individualized Electronic Intervention to Promote Work Engagement

NCT01643694

COMPLETED Phase 1

Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults

NCT01609335

TERMINATED NA

Low-dose Molecular Breast Imaging: Comparison of Breast Cancer Detection Rate at Initial Screening and Two-year Follow-up

NCT01723124

COMPLETED Phase 3

A Study Comparing Two Treatments for Child With Anxiety

NCT01624584

COMPLETED NA

Minimally Invasive Groin Dissection for Melanoma

NCT01500304

COMPLETED NA

PRevention of Acute Kidney Injury Initiated With Electronic Surveillance Enhancement

NCT01621152

COMPLETED

Maintenance Plasma Exchange for Neuromyelitis Optica

NCT01500681

COMPLETED Early Phase 1

MR-Guided Laser Ablation of Hepatic Tumors

NCT01630239

TERMINATED Phase 4

Can Nebivolol Reverse Inappropriate Left Ventricular Mass in Hypertensive Patients?

NCT01605370

TERMINATED Phase 4

Trial of Percutaneous Tibial Nerve Stimulation (PTNS) Versus PTNS and Fesoterodine Fumarate

NCT01605617

TERMINATED Phase 2

Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer

NCT01606124

TERMINATED

Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection Fraction

NCT01747785

COMPLETED

Assessing the Patient Experience in Cancer Care

NCT01621295

COMPLETED

Gene Methylation in the Diagnosis of Barrett's Esophagus: Identification of Candidate Diagnostic Markers

NCT02066701

COMPLETED Phase 4

Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery

NCT01450007

COMPLETED NA

Umbilical Cord Blood Collection and Processing for Hypoplastic Left Heart Syndrome Patients

NCT01856049

COMPLETED Phase 3

Decision Aid for Cigarette Smokers Undergoing Surgery

NCT01575119

COMPLETED Phase 4

Helping Hospitalized Patients Quit Smoking

NCT01575145

COMPLETED Phase 1

A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis

NCT01609283

COMPLETED Early Phase 1

Mobilaser Study to Help With People Who Are Having Problems With Their Gait

NCT01581645

TERMINATED Phase 3

Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

NCT01568918

TERMINATED Phase 2

Stereotactic Body Radiotherapy (SBRT) Versus Sublobar Resection for High-Risk Patients Non-Small Lung Cancer

NCT01622621

COMPLETED Phase 3

Comparison of Diaphragmatic Breathing and Muscle Relaxation for Rumination

NCT01576302

COMPLETED NA

Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation

NCT01563341

COMPLETED Phase 2

Promoting Physical Activity in Chronic Obstructive Pulmonary Disease (COPD) Through New Technology and Health Coaching

NCT01217710

COMPLETED

Histology of Functional Density in Premenopausal Breast

NCT01588834

TERMINATED Phase 1

Molecular Regulation of Muscle Glucose Metabolism

NCT01581736

TERMINATED NA

Use of Repetitive Facilitative Exercise Program in Established Stroke

NCT01574599

TERMINATED NA

Guided Self-Help for Functional Neurological Symptoms

NCT01643161

COMPLETED Phase 1

Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery

NCT01537107

COMPLETED

Breast Cancer Genome Guided Therapy Study (BEAUTY)

NCT02022202

COMPLETED Phase 1

Family Cancer Literacy to Promote Mammography Screening Among Navajo Women

NCT01605630

COMPLETED

Biomarker Feedback to Motivate Tobacco Cessation in Pregnant Alaska Native Women

NCT01605643

COMPLETED Phase 1

Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance

NCT01240252

COMPLETED NA

Does Class of Dietary Fat Affect Insulin Resistance?

NCT01541592

COMPLETED NA

Venlafaxine in Preventing Chronic Oxaliplatin-Induced Neuropathy In Patients Receiving Combination Chemotherapy

NCT01611155

COMPLETED Phase 1

Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure

NCT01544998

COMPLETED Phase 1

CR Aim #2 - AT1 Receptor Blockade & ACE Inhibition Effect on Humoral Function

NCT01678794

COMPLETED NA

Mayo Clinic Health Connection Discovery Trial

NCT01777841

TERMINATED

Development of a Psychosocial Assessment Database for Reconstructive Hand Transplantation

NCT01565187

TERMINATED Phase 4

Response of Recombinant Antithrombin in Heparin Resistant Patients Undergoing Cardiac Surgery

NCT01547728

TERMINATED Phase 1

Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) Imaging

NCT01522378

COMPLETED Phase 2

Ixazomib Citrate in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib

NCT01415882

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.