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NCT01503177 · ClinicalTrials.gov registry record · Phase 1
Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT01503177: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT01503177 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 15 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01503177, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
This phase I clinical trial investigates the side effects and the best dose of local (intrapleural measles virus therapy in treating patients with malignant pleural mesothelioma (MPM). The investigators anticipate that the intrapleural of the vaccine strain measles virus will enable the virus to specifically infect and kill cancer cells and spare, without damaging normal cells. Furthermore, the investigators expect the measles virus to trigger an anti-tumor immune response which will result in additional destruction of the tumor by immune cells
Interventions
- OTHER laboratory biomarker analysis
- PROCEDURE computed tomography
- PROCEDURE single photon emission computed tomography
- BIOLOGICAL oncolytic measles virus encoding thyroidal sodium iodide symporter
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2011-11 |
| Est. Completion | 2019-04-11 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01503177
The ClinicalTrials.gov registry entry for NCT01503177 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.
NCT01503177 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01503177 about?
NCT01503177 is a clinical study titled "Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma". This phase I clinical trial investigates the side effects and the best dose of local (intrapleural measles virus therapy in treating patients with malignant pleural mesothelioma (MPM). The investigators anticipate that the intrapleural of the vaccine strain measles virus will enable the virus to spe...
What is the current status of trial NCT01503177?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2011-11. Estimated completion is 2019-04-11.
What interventions are being tested in trial NCT01503177?
The interventions under investigation include: laboratory biomarker analysis (OTHER), computed tomography (PROCEDURE), single photon emission computed tomography (PROCEDURE), oncolytic measles virus encoding thyroidal sodium iodide symporter (BIOLOGICAL).
Who is sponsoring clinical trial NCT01503177?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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