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NCT01477164 · ClinicalTrials.gov registry record · NA
Effects of Aerobic and Resistance Training on Accumulation of Old, Modified Proteins in Young and Older Adults
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 72
- Enrollment target
NCT01477164: Completed NA study, sponsored by Mayo Clinic.
NCT01477164 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 72 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01477164, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 72 participants
- Enrollment target
Study Summary
Muscle proteins accumulate damage during aging and leads to the loss of muscle mass and function in older people. Exercise can increase the making of new proteins and removal of older proteins, but it is not known if the effect changes with aging or type of exercise. The investigators will determine the ability for endurance, resistance, or a combination of exercise training to remove older-damaged proteins and make newer-functional muscle proteins in groups of younger and older people. The investigators will particularly study protein that are involved with energy production (mitochondrial proteins) and force production (contractile proteins). Hypothesis 1: Older people will have greater accumulation of damaged proteins than younger people. Hypothesis 2: Aerobic exercise will decrease the accumulation of damaged forms of contractile and mitochondrial proteins in younger and older people. Hypothesis 3: Resistance exercise will decrease the accumulation of damaged forms of contractile proteins in younger and older people.
Interventions
- BEHAVIORAL Combined
- BEHAVIORAL High intensity aerobic exercise
- BEHAVIORAL Resistance exercise training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2011-11 |
| Est. Completion | 2017-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01477164
The ClinicalTrials.gov registry entry for NCT01477164 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 72 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Combined is the first listed.
NCT01477164 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01477164 about?
NCT01477164 is a clinical study titled "Effects of Aerobic and Resistance Training on Accumulation of Old, Modified Proteins in Young and Older Adults". Muscle proteins accumulate damage during aging and leads to the loss of muscle mass and function in older people. Exercise can increase the making of new proteins and removal of older proteins, but it is not known if the effect changes with aging or type of exercise. The investigators will determine...
What is the current status of trial NCT01477164?
This trial is currently completed. It is a NA study. The enrollment target is 72 participants. The study started on 2011-11. Estimated completion is 2017-03.
What interventions are being tested in trial NCT01477164?
The interventions under investigation include: Combined (BEHAVIORAL), High intensity aerobic exercise (BEHAVIORAL), Resistance exercise training (BEHAVIORAL).
Who is sponsoring clinical trial NCT01477164?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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