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NCT01379183 · ClinicalTrials.gov registry record · Phase 2
Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT01379183: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT01379183 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01379183, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
Magnetic Resonance Imaging (MRI) has proven to be a valuable imaging technique for suspected small bowel disease. This technique depends, in part, on adequate distension of the small bowel. This is accomplished by administering large volumes of a non-absorbable oral contrast material prior to the examination, which typically produces excellent distension of the distal small bowel and stomach, but poor distension of the proximal small bowel. Erythromycin is a common antibiotic that is known to promote stomach emptying and is used to treat diabetics with gastroparesis (poor stomach emptying.) The hypothesis of this study was that erythromycin will increase gastric emptying and hence improve small and large intestinal distention during MRI.
Primary Outcome
A Magnetic Resonance (MR) enterography procedure uses magnetic resonance imaging (MRI) technology to obtain detailed images of the small bowel. MR images of the abdomen were acquired with a torso phased array coil and a 1.5 tesla magnet MRI. Gastric volumes were assessed with an axial 3D axial gradient echo sequence, which imaged the entire stomach in 13 seconds.
Interventions
- DRUG Placebo
- PROCEDURE Magnetic Resonance Imaging
- DRUG Erythromycin
- OTHER Barium Sulfate Solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2011-06 |
| Est. Completion | 2012-03 |
| Phase | Phase 2 |
What the finished NCT01379183 record still lists
NCT01379183 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT01379183 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01379183 about?
NCT01379183 is a clinical study titled "Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility". Magnetic Resonance Imaging (MRI) has proven to be a valuable imaging technique for suspected small bowel disease. This technique depends, in part, on adequate distension of the small bowel. This is accomplished by administering large volumes of a non-absorbable oral contrast material prior to the ex...
What is the current status of trial NCT01379183?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2011-06. Estimated completion is 2012-03.
What interventions are being tested in trial NCT01379183?
The interventions under investigation include: Placebo (DRUG), Magnetic Resonance Imaging (PROCEDURE), Erythromycin (DRUG), Barium Sulfate Solution (OTHER).
Who is sponsoring clinical trial NCT01379183?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01379183's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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