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NCT02223364 · ClinicalTrials.gov registry record · Phase 4
Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
A Phase 4 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 165
- Enrollment target
NCT02223364: Completed Phase 4 study, sponsored by Mayo Clinic.
NCT02223364 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 165 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02223364, a Phase 4 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 165 participants
- Enrollment target
Study Summary
The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic nerve areas, or with actual injections in the surgical joint area with one of two different medicines, either ropivacaine or liposomal bupivacaine (Exparel®). The hypothesis was that the nerve block at the femoral and sciatic nerve areas would result in lower pain scores and opioid consumption than either of the two injections in the surgical joint area.
Primary Outcome
Pain was measured on a 1-10 numeric pain rating scale (NRS) with 0=no pain, and 10=worst pain imaginable.
Interventions
- DRUG Peripheral nerve blocks with Bupivacaine
- DRUG Intra articular injection with Ropivacaine
- DRUG Intra articular injection with liposomal bupivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2014-07 |
| Est. Completion | 2016-07 |
| Phase | Phase 4 |
What the finished NCT02223364 record still lists
NCT02223364 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 3 interventions - of which Peripheral nerve blocks with Bupivacaine is the first listed.
NCT02223364 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02223364 about?
NCT02223364 is a clinical study titled "Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)". The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic nerve areas, or with actual injections in the surgical joint area with on...
What is the current status of trial NCT02223364?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 165 participants. The study started on 2014-07. Estimated completion is 2016-07.
What interventions are being tested in trial NCT02223364?
The interventions under investigation include: Peripheral nerve blocks with Bupivacaine (DRUG), Intra articular injection with Ropivacaine (DRUG), Intra articular injection with liposomal bupivacaine (DRUG).
Who is sponsoring clinical trial NCT02223364?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02223364's enrollment target sits among peer trials
165 492nd of 2000 higher than 1,505 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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