Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 37 of 57

COMPLETED NA

Proof of Concept: "Bottom's Up" Seat to Treat Constipation

NCT02419924

COMPLETED NA

Mindfulness Based Resilience Training

NCT02419430

COMPLETED NA

Pilot Study Testing Feasibility of Health Screening at Farm Site

NCT02418637

TERMINATED Phase 2

MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer

NCT02364713

COMPLETED Phase 2

Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT01806571

COMPLETED Phase 3

Pilot Study of ACTH in the Treatment of Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

NCT02282930

COMPLETED NA

Optimizing the Management of Flares in Patients With Rheumatoid Arthritis (RA)

NCT02382783

COMPLETED NA

Exparel Transversus Abdominis Plane Block vs Intrathecal Analgesia In Colorectal Surgery

NCT02356198

COMPLETED Phase 2

Biomarker Feedback to Motivate Cessation in Pregnancy

NCT02431611

TERMINATED Phase 4

16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression

NCT02389712

COMPLETED Phase 2

Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas

NCT02332980

TERMINATED Phase 3

Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma

NCT02320292

COMPLETED NA

A PK/PD Genetic Variation Treatment Algorithm Versus Treatment As Usual for Adolescent Management Of Depression

NCT02286440

COMPLETED NA

Gut Permeability, Sensitivity and Symptomatology

NCT02358564

COMPLETED NA

Optimizing Sleep/Wake Related Cognitive Efficacy

NCT02412410

COMPLETED Phase 4

Early Diuresis Following Colorectal Surgery

NCT02351934

COMPLETED NA

Shared Decision Making With Pharmaceutical Care

NCT02373059

COMPLETED NA

Fostering Resilience in Physician Moms

NCT02540473

COMPLETED NA

Novel Support Options in Autologous Stem Cell Transplant for Multiple Myeloma

NCT02274519

TERMINATED NA

Electronic Nose Identification of Fasting and Non-fasting Breath Profiles

NCT02419976

COMPLETED Early Phase 1

MART-1 Antigen With or Without TLR4 Agonist GLA-SE in Treating Patients With Stage II-IV Melanoma That Has Been Removed by Surgery

NCT02320305

COMPLETED NA

Microbreaks in the OR to Mitigate High Physical and Mental Demands

NCT02565394

COMPLETED NA

Statin Choice Decision Aid Implementation First Phase

NCT02375815

COMPLETED Early Phase 1

The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis

NCT02353078

TERMINATED Phase 1

Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)

NCT01978535

COMPLETED NA

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

NCT02089217

COMPLETED Phase 1

Alisertib and Fulvestrant in Treating Patients With Hormone Receptor Positive Breast Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

NCT02219789

COMPLETED

Microbiome of Depression & Treatment Response to Citalopram

NCT02330068

COMPLETED Phase 1

Progesterone Amplifies Estrogen-stimulated Growth Hormone Secretion in Older Women

NCT02272647

COMPLETED Phase 4

Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage

NCT02330094

COMPLETED

New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease

NCT02250287

COMPLETED Phase 2

Ponatinib Hydrochloride in Treating Patients With Advanced Biliary Cancer With FGFR2 Fusions

NCT02265341

COMPLETED NA

Nurse-led Patient-centered Advance Care Planning: A Pilot Study

NCT02302820

COMPLETED Phase 1

Estradiol-Receptor Blockade in Older Men and Women

NCT02271282

COMPLETED Early Phase 1

Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study

NCT02318433

COMPLETED Phase 2

Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

NCT02283658

COMPLETED NA

Short Versus Long Cephalomedullary Nailing of Pertrochanteric Hip Fractures: A Randomized Prospective Study

NCT02285127

COMPLETED NA

A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of Depression

NCT02189057

COMPLETED NA

The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.

NCT02285634

COMPLETED NA

Development of a Youth Healthy Living Program With Underserved Adolescents at Rochester Alternative Learning Center

NCT02289313

COMPLETED Phase 2

Pilot Study of Rituximab to Treat Fibrillary Glomerulonephritis

NCT02197767

COMPLETED Phase 1

Hypoxia and Inflammatory Injury in Human Renovascular Hypertension

NCT02266394

COMPLETED Phase 4

Study of Exparel Versus Epidural for Pain Control After Thoracotomy

NCT02178553

COMPLETED

An Integrated Approach to Treating Recurrent Thoracic Carcinomas Resistant to Tyrosine Kinase Inhibitors

NCT02616211

COMPLETED

CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification

NCT02245048

COMPLETED

Assessment of Wall Thickness in Hypertrophic Cardiomyopathy

NCT02234336

COMPLETED NA

Pilot Project on External Vestibular Prosthesis in Chronic Subjective Dizziness

NCT02048670

COMPLETED NA

Home Telemonitoring in Patients at High Risk for Readmission

NCT02136186

COMPLETED Phase 2

Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction

NCT02262078

COMPLETED

Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome

NCT02249169

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.