Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 20 of 57

COMPLETED NA

Wearable Technology in Endoscopy

NCT05044104

COMPLETED Phase 1

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

NCT05130060

COMPLETED NA

Study of Intra-Cardiac Echocardiography in Guiding Left Atrial Appendage Occlusion With the Watchman Device

NCT05136417

COMPLETED

Remote Monitoring in Cancer Care: A Platform Study

NCT05018208

COMPLETED NA

Home-based Pulmonary Rehabilitation and Health Coaching in Fibrotic Interstitial Lung Disease

NCT05130034

COMPLETED NA

Acupuncture Therapy for COVID-Related Olfactory Loss

NCT04952389

COMPLETED

Educational Materials for Hiccups

NCT05313685

COMPLETED

A Study to Evaluate ICU Simulation Experience in the Cardiothoracic Surgical Population to Reduce Post-operative Delirium

NCT05159648

COMPLETED

Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk

NCT05214573

COMPLETED NA

Correlation of Spinopelvic Movement With Lateral Radiographs

NCT05117229

COMPLETED Phase 2

Practical Anemia Bundle for SusTained Blood Recovery

NCT05167734

COMPLETED NA

Virtual Dignity Therapy for Palliative Care Patients With Advanced Cancer

NCT05113199

COMPLETED Phase 2

Obinutuzumab in Primary FSGS

NCT04983888

COMPLETED

Non-invasive Biomarkers of Metabolic Liver Disease (NIMBLE) Study 1.2

NCT05081427

TERMINATED

Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity

NCT04837183

COMPLETED NA

Use of the OPTIMAL Theory of Motor Learning With the Lower Quarter Y-Balance Test

NCT05113797

COMPLETED

Performance and Accuracy of an AI Enhanced Smart Watch Single Lead ECG

NCT05450809

COMPLETED NA

The Burden of COVID-19 Survivorship

NCT04913129

COMPLETED NA

Burnout Reduction and Engagement App-based Trial of Headspace (BREATHE)

NCT05036356

COMPLETED NA

Evaluating Mindfulness-Based Interventions With New Fibromyalgia Patients

NCT04720053

COMPLETED NA

Mayo Clinic Family Medicine Resident Wellness Study

NCT05148221

COMPLETED NA

Covid-19 Virtual Recovery Study

NCT04950725

TERMINATED NA

Enhancing Facial Nerve Function With Omega-3 After Resection of Vestibular Schwannoma

NCT05116878

COMPLETED

Comparison of Onset of Neuromuscular Blockade With Electromyographic and Acceleromyographic Monitoring

NCT05120999

COMPLETED Phase 4

Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty

NCT05005260

COMPLETED

Brain and Abdominal Aneurysm Study

NCT01420991

COMPLETED NA

Regulation of Muscle Protein Phenotype in Humans With Obesity

NCT04700800

COMPLETED

Sleep Apnea in Heart Failure With Preserved Ejection Fraction

NCT05008432

COMPLETED Phase 2

Microscopic Fluorescence-guided Vestibular Schwannoma Resection Using Fluorescein Sodium and YELLOW 560

NCT04351373

COMPLETED NA

Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

NCT05047926

TERMINATED NA

Smartphone-based Virtual Reality Exposure and Standard Relaxation Training for Anxiety on an Inpatient Psychiatric Unit

NCT05050123

COMPLETED

Development of an EEG Diagnostic for Alzheimer's Disease

NCT04954183

COMPLETED Phase 4

Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis

NCT04801368

TERMINATED Phase 1

Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)

NCT05457491

TERMINATED NA

Three Good Things (3GT) - Intervention for Transitional Care Patients

NCT04970641

COMPLETED

Oropharynx (OPX) Salivary Biomarker Study

NCT05093400

TERMINATED Phase 1

Ipilimumab and Nivolumab for the Treatment of Stage III-IV Unresectable Metastatic Melanoma

NCT04967196

COMPLETED Phase 1

Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

NCT03887741

COMPLETED NA

A Study to Assess the Effect of Smart Insulin Pens on Glycemic Control and Diabetes-related Burdens

NCT05036343

COMPLETED

Self-Obtained Ultrasound Scans for Measurement of Cervical Dilation and Effacement in Labor

NCT05038891

COMPLETED NA

A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease

NCT04960280

COMPLETED NA

The Effects of Synaquell on Brain Function

NCT05041192

COMPLETED NA

Cardiac Rehab and Cerebral Blood Flow Study

NCT05012878

COMPLETED

A Multi-Center Study of Detection of Low Ventricular Ejection Fraction

NCT04963218

COMPLETED NA

Improving Wellbeing in Ischemic Heart Disease

NCT04974541

TERMINATED NA

Digital Photography to Estimate Anthropometric Measurements in Children

NCT05034913

COMPLETED Phase 1

Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration

NCT04673877

TERMINATED Phase 2

Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer

NCT04805788

COMPLETED

Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation

NCT04992676

COMPLETED Early Phase 1

3D Ultrasound Microvessel Imaging for Breast Masses

NCT04925817

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.