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NCT03887741 · ClinicalTrials.gov registry record · Phase 1

Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

A Phase 1 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 1
Development phase
3
Enrollment target

NCT03887741: Completed Phase 1 study, sponsored by Mayo Clinic.

NCT03887741 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT03887741, a Phase 1 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

Determine safety of plasma infusion or exchange in APOE 44 patients.

Primary Outcome

Number of adverse events reported

Interventions

  • BIOLOGICAL Plasmapheresis
  • BIOLOGICAL Plasma infusion

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2021-09-15
Est. Completion 2024-02-16
Phase Phase 1
Mayo Clinic

2,844 total trials

What the finished NCT03887741 record still lists

NCT03887741 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Plasmapheresis is the first listed.

NCT03887741 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03887741 about?

NCT03887741 is a clinical study titled "Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression". Determine safety of plasma infusion or exchange in APOE 44 patients.

What is the current status of trial NCT03887741?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2021-09-15. Estimated completion is 2024-02-16.

What interventions are being tested in trial NCT03887741?

The interventions under investigation include: Plasmapheresis (BIOLOGICAL), Plasma infusion (BIOLOGICAL).

Who is sponsoring clinical trial NCT03887741?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03887741's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03887741, the US trial registry maintained by the National Library of Medicine. NCT03887741 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.