Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 19 of 57

TERMINATED Phase 2

Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma

NCT05288062

COMPLETED Phase 2

Topical Cannabidiol for the Treatment of Chemotherapy-Induced Peripheral Neuropathy

NCT05388058

COMPLETED NA

Low-level Laser and Lifestyle Modifications

NCT05083442

COMPLETED NA

Mindfulness Intervention for Post-Covid Symptoms

NCT05199233

COMPLETED Phase 1

Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults

NCT04996719

COMPLETED NA

Regenerative Medicine Approach to Nasal Reconstruction

NCT05273060

COMPLETED Phase 3

68Ga-PSMA-11 PET/CT Screening Prior to 177Lu-PSMA-617 Therapy for Patients With Metastatic Castrate Resistant Prostate Cancer

NCT05547386

COMPLETED NA

A Pilot Study Using Facebook to Support Opioid Recovery Among American Indian Women

NCT05340855

COMPLETED NA

Dual-plane Ultrasound Imaging During Vascular Access Procedures

NCT05093699

COMPLETED

Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine

NCT05012358

TERMINATED NA

Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder

NCT05307770

TERMINATED Phase 2

COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes

NCT04537299

COMPLETED NA

Healthy Immigrant Community: Mobilizing the Power of Social Networks

NCT05136339

COMPLETED

Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients

NCT05654493

COMPLETED NA

IBD and Women's Health Wellness Program

NCT05172557

COMPLETED Phase 3

A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

NCT05053087

COMPLETED Phase 2

Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis

NCT05160532

COMPLETED

A Study to Detect Hyperkalemia Using Smartphone-enabled Electrocardiogram (EKG)

NCT05441852

COMPLETED Phase 4

Clopidogrel Monotherapy in Patients With High Bleeding Risk

NCT05223335

TERMINATED NA

A Study to Evaluate SU-VEID™ for Improving Peripheral Venous Access Success in Children

NCT05204082

COMPLETED

Maternal-fetal Immune Responses to Fetal Surgery

NCT04484441

COMPLETED NA

Monitoring of Sleep and Behavior of Children 3-7 Years Old Receiving Parent-Child Interaction Therapy With the Help of Artificial Intelligence

NCT05077722

COMPLETED NA

Development of Technologies to Increase In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users

NCT04934137

COMPLETED

Infiltration of Gadolinium Injection in Brain MR Scans Using Artificial Intelligence

NCT05235646

COMPLETED Phase 4

Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee Arthroplasty

NCT05188053

COMPLETED

A Study to Evaluate Spine Motion in Older Adults

NCT05364320

COMPLETED Phase 1

PRP for the Treatment of Erectile Dysfunction (ED)

NCT04350125

COMPLETED

Evaluating Patient Reported Outcomes in Radiation Therapy, the PRO-RT Study

NCT05224271

COMPLETED

Determinants and Effects in the Use of NOHARM Pain Management

NCT05166356

COMPLETED

A Pilot Study to Test the Acceptability and Feasibility of Relaxation Rooms to Help Reduce Occupational Stress Among Healthcare Workers

NCT05134155

COMPLETED NA

Tonation Breathing Technique Method to Ease Aromatase Inhibitor-induced Joint and/or Muscle Pain

NCT05412953

COMPLETED

Developing a Shared Decision Making Tool for Patients With Surgically Removed Non-small Cell Lung Cancer

NCT05416983

COMPLETED NA

Allergy Skin Patch Artificial Intelligence (AI)

NCT05339750

TERMINATED NA

Effect of Advanced Care at Home vs. Traditional Brick-and-Mortar Hospital Care in Acutely Ill Adults: A Randomized Clinical Trial

NCT05212077

COMPLETED

Recovery of Respiratory System in COVID-19 Patients

NCT04954222

COMPLETED NA

Increasing Digital Equity and Access Among Rural Patients (IDEA) Study

NCT05209451

COMPLETED

The Role of Interferon-gamma in Immune Responses to Invasive Candidiasis

NCT05235711

TERMINATED NA

Adaptive Virtual Consultation Tool to Enhance Education and Understanding in Patients with Prostate Cancer

NCT06016504

COMPLETED NA

Physical Activity Intervention for Hematopoietic Cell Transplant Recipients and Caregivers

NCT05208554

COMPLETED NA

Variability in Spinopelvic Parameters Among Patients Undergoing Total Hip Arthroplasty

NCT05212090

COMPLETED Phase 2

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

NCT05176223

COMPLETED

Immunophenotyping in Metastatic Kidney Cancer Patients Receiving Ablative Therapy

NCT05112627

COMPLETED NA

Care Anywhere With Community Paramedics Program to Reduce Hospitalization

NCT05232799

COMPLETED

Supraglottic Airway Needed To Achieve Ventilation

NCT05190757

COMPLETED NA

Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation

NCT05045079

COMPLETED

Long-term Effects of COVID-19

NCT05220514

COMPLETED NA

A Study to Evaluate Liver Stiffness With Shear Wave Elastography

NCT05097963

COMPLETED NA

A Study of Acute Kidney Injury in Care Transitions

NCT05184894

COMPLETED NA

Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques

NCT05006443

TERMINATED Phase 2

Education for Prevention of Melanoma in Hispanic Populations

NCT05388851

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.