Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 21 of 57

COMPLETED NA

Pap Smear Collection With the Papette Brush

NCT05034614

COMPLETED Phase 2

Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer

NCT04828486

COMPLETED

Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study

NCT05053100

COMPLETED NA

A Study to Asses Wellness Using a Brain Sensing Device on Physicians

NCT04743973

COMPLETED Phase 3

A Home-based Module to Promote Mindful Breathing Awareness for COPD Patients

NCT04517500

TERMINATED Phase 2

Erenumab For Treatment of Hemicrania Continua

NCT04303845

COMPLETED NA

UC Cohort - The Influence of Diet on Gut Microbiotas

NCT04933162

COMPLETED

Evaluating Clinical Evaluation Tools for Predicting Risk of Complications After Hematopoietic Stem Cell Transplant

NCT05766332

COMPLETED NA

Assessment of Research Digest Impact for Minority with Prostate Cancer, MiCAP Phase III Study

NCT05895279

COMPLETED Phase 2

Spasmodic Dysphonia Pain

NCT04648891

COMPLETED NA

Noninvasive Evaluation of Renal Allograft Fibrosis by MRI

NCT04899167

TERMINATED Phase 2

Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk

NCT04570956

COMPLETED NA

Learning From Our Patients, Learning From Our Practice: Implementing an Intervention to Support Patients on Dialysis

NCT04924582

COMPLETED NA

AI Driven Biofeedback Wearable

NCT04921410

COMPLETED NA

Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)

NCT04938661

COMPLETED Early Phase 1

Effects of Probiotics on the Gut Microbiome and Immune System in Operable Stage I-III Breast or Lung Cancer

NCT04857697

COMPLETED

Identification of Non-gal, Non-HLA Antigens in Patients Implanted With Xenogenic Material

NCT04938960

COMPLETED NA

Eye Tracking in Laryngology

NCT05034575

COMPLETED NA

The Impact of the Certified Child Life Specialist on Children's Pain During Immunizations

NCT05285254

TERMINATED NA

Manipulating and Optimizing Brain Rhythms for Enhancement of Sleep

NCT05089682

COMPLETED

Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy

NCT04688125

COMPLETED NA

A Study to Evaluate the Influence of Diet on GI Health

NCT04783142

TERMINATED Phase 1

Belantamab Mafodotin, Lenalidomide, and Daratumumab for the Treatment of Relapsed, Refractory, or Previously Untreated Multiple Myeloma

NCT04892264

COMPLETED

COVID-19 Infection in Patients Receiving Anti-CD20 Therapy

NCT04884477

COMPLETED NA

Eosinophils in Human Adipose Tissue

NCT04898400

COMPLETED NA

A Study to Evaluate the Effects of Sharpened Romberg Testing (SRT) in Healthy Subjects

NCT04897360

COMPLETED Early Phase 1

Ultrasound-guided Erector Spinae Plane Blocks

NCT04916691

COMPLETED NA

Physiological Validation of Current Machine Learning Models for Hemodynamic Instability in Humans

NCT03927066

COMPLETED NA

Implementing Shared Decision Making (SDM) For Individualized CV Prevention (SDM4IP)

NCT04450914

COMPLETED Phase 2

PET Imaging to Delineate Macrophage Activation in Diabetic Gastroparesis

NCT04762719

COMPLETED

Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App

NCT05324566

COMPLETED Phase 4

A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes

NCT04481243

COMPLETED

Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Device in the Diagnosis of Obstructive Sleep Apnea

NCT04778748

COMPLETED NA

Post-Surgical Based Efforts to Reduce Preventable Readmissions and Optimize Length of Stay

NCT04881708

COMPLETED NA

Use of an Innovative Mobile Health Intervention to Improve Hypertension Among African-Americans

NCT04554147

TERMINATED NA

The Role of the Pharmacist and Pharmacogenomics in the Care of Seriously Ill Patients

NCT04251520

COMPLETED NA

New Reusable Mask Design With Superior Filtration and Fit

NCT04826809

COMPLETED NA

Vascular Anomaly Pathology and Genomics Biopsy Study

NCT04836884

COMPLETED NA

Equitable Access to COVID-19 Vaccines

NCT04952376

COMPLETED

Metabolite Levels in Ovarian Cancer Patients Receiving Maintenance PARP Inhibitors

NCT04917744

COMPLETED

Multiscale Omics for the Development of a Cohort Database and Study Platform in Breast Cancer Survivors

NCT04999826

COMPLETED

Efficacy and Safety of COVID-19 Vaccine in Cancer Patients

NCT04865133

TERMINATED NA

A Study to Evaluate Visually Inspired Patient Education Material on Willingness to Pursue Radiation Therapy

NCT04839679

COMPLETED NA

The Impact of Integrative Medicine on Patient-Reported Outcomes in Management of Chronic Pelvic Pain

NCT04773925

COMPLETED NA

Enabling Independent Living by Expanding Access to Home-Based Pulmonary Rehabilitation

NCT04479969

COMPLETED

Endoprosthesis Metal Toxicity Study

NCT04755140

TERMINATED Phase 2

Acetazolamide Efficacy in Ataxia in PMM2-CDG

NCT04679389

COMPLETED NA

Non-pharmaceutical Motion Sickness Mitigation

NCT04859868

COMPLETED

Effects of Pulmonary Hypertension Therapy in Atypical Pulmonary Arterial Hypertension

NCT04787445

COMPLETED Phase 4

Intrathecal Opioids for Colorectal Resection

NCT04752033

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.