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NCT05012878 · ClinicalTrials.gov registry record · NA

Cardiac Rehab and Cerebral Blood Flow Study

A NA study, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
45
Enrollment target

NCT05012878: Completed NA study, sponsored by Mayo Clinic.

NCT05012878 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 45 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT05012878, a NA study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
45 participants
Enrollment target

Study Summary

This study is being done to better understand the influence of cardiovascular disease on brain blood flow regulation and cognitive function, determine whether exercise-based cardiac rehabilitation can lead to better regulation of brain blood flow that may help to improve or maintain cognitive function, and determine whether exercise intensity influences changes in brain blood flow regulation and cognitive function.

Primary Outcome

Measured as the change in cerebral blood flow during a stepped protocol of increases in inhaled carbon dioxide concentrations. Reactivity will be measured as the regression slope of cerebral blood flow velocity (cm per second) per mmHg increase in end-tidal carbon dioxide.

Interventions

  • BEHAVIORAL Cardiac rehabilitation - high intensity interval training (HIIT)
  • BEHAVIORAL Cardiac rehabilitation - moderate intensity continuous training (MICT)
  • BEHAVIORAL Cardiac rehabilitation - control
  • BEHAVIORAL Cardiac rehabilitation - observational

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2021-09-02
Est. Completion 2025-04-23
Phase NA
Mayo Clinic

2,844 total trials

What the finished NCT05012878 record still lists

NCT05012878 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 4 interventions - of which Cardiac rehabilitation - high intensity interval training (HIIT) is the first listed.

NCT05012878 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05012878 about?

NCT05012878 is a clinical study titled "Cardiac Rehab and Cerebral Blood Flow Study". This study is being done to better understand the influence of cardiovascular disease on brain blood flow regulation and cognitive function, determine whether exercise-based cardiac rehabilitation can lead to better regulation of brain blood flow that may help to improve or maintain cognitive functi...

What is the current status of trial NCT05012878?

This trial is currently completed. It is a NA study. The enrollment target is 45 participants. The study started on 2021-09-02. Estimated completion is 2025-04-23.

What interventions are being tested in trial NCT05012878?

The interventions under investigation include: Cardiac rehabilitation - high intensity interval training (HIIT) (BEHAVIORAL), Cardiac rehabilitation - moderate intensity continuous training (MICT) (BEHAVIORAL), Cardiac rehabilitation - control (BEHAVIORAL), Cardiac rehabilitation - observational (BEHAVIORAL).

Who is sponsoring clinical trial NCT05012878?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05012878's enrollment target sits among peer trials

45 1411th of 2000 higher than 578 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05012878, the US trial registry maintained by the National Library of Medicine. NCT05012878 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.