Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 1 of 41
Sauna for Long Covid
NCT05931497
HIPS Feasibility Randomized Controlled Trial
NCT07586397
Increasing Resiliency Among Early Post-Treatment Lymphoma Survivors
NCT07014293
BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention
NCT07162337
Time Restricted Eating (TRE) in Bipolar Disorder
NCT07211217
Symptom Monitoring With Supported Feedback in Advanced Chronic Kidney Disease
NCT07186218
EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)
NCT07202000
A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer
NCT07513311
A Natural History Study of Angelman Syndrome
NCT07417137
Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism
NCT07649161
SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial
NCT06674109
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
NCT07128355
Video Inspired Discussions About Ethical Outcomes in Pediatrics
NCT06786104
Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease
NCT07568509
Effects of Resistance Exercise Among TGD Individuals Initiating Estrogen-Based Gender-Affirming Hormone Therapy
NCT07400419
Development and Testing of a Mobile App to Scale Delivery of Cognitive-behavioral Therapy for Avoidant/Restrictive Food Intake Disorder
NCT06898177
Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
NCT07236190
Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression
NCT07563868
Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis
NCT06691217
Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia
NCT07238400
Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients
NCT06751992
Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors
NCT07414732
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
NCT07269808
Pilot Study of a Brain Health Program in Senior Centers
NCT07424443
Finding Links Between Hot flASHes and CardioVascular Disease
NCT07077395
Promoting Recovery After Brain Injury Using Focused Ultrasound
NCT07277309
LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia
NCT07417163
Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs
NCT07199335
Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
NCT07095517
iNO300 Therapy in Critically Ill Patients With Pneumonia
NCT06950294
Improving Outcomes of Older Adults Undergoing Ostomy Surgery
NCT07424586
A Prospective Longitudinal Observational Cohort Study of Pregnant Women Residing at High Altitude in Bolivia
NCT07312227
A Digital Health Intervention to Improve Physical Function and Wellness of Lung Cancer Survivors
NCT07227623
Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital
NCT07359157
Voice Therapy Per the Rehabilitation Treatment Specification System
NCT06152627
Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
NCT06878859
Assessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-Schwannomatosis
NCT07420751
Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners
NCT07018726
Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver
NCT07364474
A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
NCT06967545
Ivosidenib as Post-HSCT Maintenance for AML
NCT06707493
VGAIT for Chemotherapy-induced Peripheral Neuropathy
NCT07177820
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2
NCT07166861
Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation
NCT06676852
Momelotinib During and After HCT in Myelofibrosis
NCT07104799
Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy
NCT07233408
Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares
NCT07346079
Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma
NCT07032714
Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment
NCT07226947
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
NCT07102797
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.