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NCT07104799 · ClinicalTrials.gov registry record · Phase 1

Momelotinib During and After HCT in Myelofibrosis

A Phase 1 study of Myelofibrosis and Hematopoietic Cell Transplantation (HCT), sponsored by Massachusetts General Hospital.

Recruiting
Registry status
Phase 1
Development phase
28
Enrollment target
1
Study location

NCT07104799 is a Phase 1 study of Myelofibrosis and Hematopoietic Cell Transplantation (HCT) that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 28 participants, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07104799, a Phase 1 study of Myelofibrosis and Hematopoietic Cell Transplantation (HCT), is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
Phase 1
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT).

Interventions

  • DRUG Momelotinib

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2026-01-01
Est. Completion 2030-01
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT07104799

The ClinicalTrials.gov registry entry for NCT07104799 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 195-participant average among 61 other Myelofibrosis trials with a reported enrollment target (86% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Myelofibrosis appearing as the primary indexed condition, and to 1 intervention - of which Momelotinib is the first listed.

NCT07104799 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07104799 about?

NCT07104799 is a clinical study titled "Momelotinib During and After HCT in Myelofibrosis". This is a single-center, open-label, phase I study to determine the safety and tolerability of momelotinib in patients with myelofibrosis during and after hematopoietic cell transplantation (HCT).

What is the current status of trial NCT07104799?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2026-01-01. Estimated completion is 2030-01.

What conditions does trial NCT07104799 study?

This clinical trial studies the following conditions: Myelofibrosis, Hematopoietic Cell Transplantation (HCT).

What interventions are being tested in trial NCT07104799?

The interventions under investigation include: Momelotinib (DRUG).

Who is sponsoring clinical trial NCT07104799?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07104799 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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