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NCT07359157 · ClinicalTrials.gov registry record · NA
Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital
A NA study of Depression and Serious Mental Illness, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07359157: Recruiting NA study of Depression and Serious Mental Illness, sponsored by Massachusetts General Hospital.
NCT07359157 is a NA study of Depression and Serious Mental Illness that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 40 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07359157, a NA study of Depression and Serious Mental Illness, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
People with serious mental illness (depression, bipolar, and schizophrenia spectrum disorders) have high rates of repeated criminal legal involvement and psychiatric hospitalizations. Longstanding research shows that in addition to treating clients' symptoms of mental illness, targeting risk factors for legal involvement can help reduce their chances of future incarcerations. Because hospitals are becoming increasingly forensic, treatment programs that address both mental illness and risk factors for legal involvement may be especially helpful in a state hospital setting, like Worcester Recovery Center and Hospital (WRCH). This treatment study offers an adjunctive 9-session intervention, Changing Lives and Changing Outcomes-9 (CLCO-9), for patients at WRCH; this program is designed to help people with serious mental illness who are involved in the legal system increase their awareness of their mental health and reduce their chances of future legal involvement. The investigators are proposing a treatment study testing the use of the CLCO-9 group intervention with patients with serious mental illness with current or previous criminal legal involvement at Worcester Recovery Center and Hospital (WRCH). The study has three aims: 1. Evaluate feasibility, fidelity, and patient satisfaction during the implementation of the CLCO-9 group treatment at WRCH 2. Evaluate CLCO-9's effectiveness on improving patient's self-reported mental health, and behavioral indicators of mental health and risk factors for legal involvement 3. Explore changes in WRCH clinicians' knowledge and attitudes about treating risk factors for criminal legal involvement. To test these aims, the research team will employ a two-phase study. In the first phase, the researchers will implement the intervention and make necessary adjustments to maximize the success of the implementation. In the second phase, the researchers will evaluate the treatment program's effectiveness in producing change from pre- to
Primary Outcome
aggression and hostility
Conditions Studied
Interventions
- BEHAVIORAL Changing Lives and Changing Outcomes-9
Study Locations (1)
Massachusetts
- Worcester Recovery Center and Hospital - Worcester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-02-05 |
| Est. Completion | 2026-07-01 |
| Phase | NA |
What NCT07359157 shows while recruiting
NCT07359157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower).
The record links to 4 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Changing Lives and Changing Outcomes-9 is the first listed.
NCT07359157 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07359157 about?
NCT07359157 is a clinical study titled "Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital". People with serious mental illness (depression, bipolar, and schizophrenia spectrum disorders) have high rates of repeated criminal legal involvement and psychiatric hospitalizations. Longstanding research shows that in addition to treating clients' symptoms of mental illness, targeting risk factors...
What is the current status of trial NCT07359157?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-02-05. Estimated completion is 2026-07-01.
What conditions does trial NCT07359157 study?
This clinical trial studies the following conditions: Depression, Serious Mental Illness, Psychotic Disorder, Bipolar.
What interventions are being tested in trial NCT07359157?
The interventions under investigation include: Changing Lives and Changing Outcomes-9 (BEHAVIORAL).
Who is sponsoring clinical trial NCT07359157?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07359157 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07359157's enrollment target sits among peer trials
40 509th of 679 higher than 151 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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