Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07277309 · ClinicalTrials.gov registry record · NA
Promoting Recovery After Brain Injury Using Focused Ultrasound
A NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 2
- Study locations
NCT07277309 is a NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 36 participants, below the 54-participant average among 4 other Consciousness Disorders trials with a reported enrollment target (33% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT07277309, a NA study of Consciousness Disorders and Disorders of Consciousness Due to Severe Brain Injury, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 2
- Study locations
Study Summary
The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this project aims to (1) determine neurobehavioral responses to low-intensity focused ultrasound (LIFUP) in patients with disorders of consciousness (DoC) following brain injury, (2) determine neurophysiologic (EEG) responses to LIFUP in patients with DoC and (3) identify and evaluate ethical perspectives of patient representatives (family members and surrogate decision-makers) surrounding investigation of therapeutic neuromodulation technologies such as LIFUP in patients with DoC.
Conditions Studied
Interventions
- DEVICE Low-intensity focused ultrasound
Study Locations (2)
Massachusetts
- Massachusetts General Hospital (The General Hospital Corp.) - Boston
- Spaulding Rehabilitation Hospital Corporation, Inc. - Cambridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-03 |
| Est. Completion | 2029-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07277309
The ClinicalTrials.gov registry entry for NCT07277309 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 54-participant average among 4 other Consciousness Disorders trials with a reported enrollment target (33% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Consciousness Disorders appearing as the primary indexed condition, and to 1 intervention - of which Low-intensity focused ultrasound is the first listed.
NCT07277309 reports 2 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT07277309 about?
NCT07277309 is a clinical study titled "Promoting Recovery After Brain Injury Using Focused Ultrasound". The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover. In particular, this project aims to (1) determine neurobehavioral responses to low-intensity focused ultrasound (LIFUP) in patients with disorder...
What is the current status of trial NCT07277309?
This trial is currently recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2026-03. Estimated completion is 2029-07.
What conditions does trial NCT07277309 study?
This clinical trial studies the following conditions: Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury.
What interventions are being tested in trial NCT07277309?
The interventions under investigation include: Low-intensity focused ultrasound (DEVICE).
Who is sponsoring clinical trial NCT07277309?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07277309 being conducted?
This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Consciousness Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU
RECRUITING · NA
-
Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness
RECRUITING · NA
-
Ultrasound Stimulation for Patients in a Disorder of Consciousness
RECRUITING · NA
-
Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome
COMPLETED · NA
Explore more on PlainTrial
Consciousness Disorders
All registered trials for this condition
Disorders of Consciousness Due to Severe Brain Injury
All registered trials for this condition
Massachusetts
All trials with a study site in Massachusetts
Recruiting now
Find trials open to new participants near you
Rankings
Top sponsors, conditions, and phases
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.