Massachusetts Eye and Ear Infirmary

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts Eye and Ear Infirmary sits in the top decile of US sponsors by registered trial count (#295 of 15,742 sponsors by registered trial count).

73 total trials 20 currently recruiting 36 completed early-phase tilt top decile by trial count

Massachusetts Eye and Ear Infirmary: 73 sponsored US clinical trials, 20 recruiting.

Massachusetts Eye and Ear Infirmary sponsors 73 registered US clinical trials on ClinicalTrials.gov, 20 of them currently recruiting, and 36 completed. 8 of these trials are in Phase 3-4 (later-stage) and 22 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Spasmodic Dysphonia, with 4 trials.

Top-decile sponsor footprint

Massachusetts Eye and Ear Infirmary ranks in the top decile of sponsors by registered trial count (#295 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

36 of 44 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

73 total, page 1 of 2

RECRUITING NA

Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

NCT06688578

RECRUITING NA

The Glaucoma and Retinopathy Screening Study

NCT06882356

RECRUITING Phase 2

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

NCT06753916

RECRUITING

ctDNA in Cutaneous Squamous Cell Carcinoma

NCT06875609

RECRUITING NA

A Trial of Hydrus Microstent Versus Goniotomy

NCT06289491

RECRUITING

Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck

NCT06744296

RECRUITING Phase 1

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

NCT06033703

RECRUITING NA

Reminder-cue Scanning Training for Homonymous Visual Field Loss

NCT06136169

RECRUITING NA

Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping Strategy

NCT06960616

RECRUITING

Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor

NCT05150106

RECRUITING NA

Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

NCT05867173

RECRUITING Phase 4

Dropless Pars Plana Vitrectomy Study

NCT05331664

RECRUITING NA

Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor

NCT05150093

RECRUITING NA

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

NCT05317390

RECRUITING Early Phase 1

Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor

NCT05216770

RECRUITING Phase 1

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

NCT04225611

RECRUITING Phase 2

Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD

NCT04735263

RECRUITING NA

Feasibility Tests for Various Prism Configurations for Visual Field Loss

NCT04424979

RECRUITING Phase 2

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

NCT04440280

RECRUITING

Brain Networks in Dystonia

NCT03042962

ACTIVE NOT RECRUITING NA

Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision

NCT06024668

ACTIVE NOT RECRUITING

Assessing the Utility of Plasma ctHPVDNA for Anal Cancer Screening

NCT06971276

ACTIVE NOT RECRUITING NA

Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia

NCT04827147

ACTIVE NOT RECRUITING Phase 1

Doxycycline in Cutaneous Schwannoma (NF2)

NCT05521048

ACTIVE NOT RECRUITING NA

Feasibility Test of Virtual Reality Obstacle Detection for Low Vision Walking

NCT05141604

ACTIVE NOT RECRUITING Phase 2

Lenvatinib in Locally Advanced Invasive Thyroid Cancer

NCT04321954

ACTIVE NOT RECRUITING Phase 2

Study of Aspirin in Patients With Vestibular Schwannoma

NCT03079999

NOT YET RECRUITING Phase 2

Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema

NCT07383701

NOT YET RECRUITING Phase 1

Subconjunctival Humira for Boston Keratoprosthesis

NCT06926478

TERMINATED Phase 1

Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension

NCT04500574

COMPLETED NA

Multiplexing Prism Fitting for Field Expansion of Monocular Vision

NCT06027216

COMPLETED NA

Understanding Visual Confusion Using Stereoscopic Displays

NCT04957745

COMPLETED NA

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

NCT04678115

COMPLETED Early Phase 1

Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty

NCT04752020

COMPLETED Phase 2

Anti-VEGF Therapy for Acute Thyroid Eye Disease

NCT04311606

COMPLETED

ctDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPVca)

NCT06730412

COMPLETED NA

A Comparison of the Effect of Suture Material on Blepharoplasty Incision

NCT04585217

COMPLETED NA

Clinical Trial to Improve the Magnetic Levator Prosthesis

NCT03818204

COMPLETED Early Phase 1

Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty

NCT04057053

COMPLETED

Mobile Medical Application for Cost-effective Strabismus Screening

NCT03450980

COMPLETED NA

Collision Warning Device for Blind and Visually Impaired

NCT03057496

COMPLETED

Perioperative Complications of Deep Extubation in Adults

NCT04557683

COMPLETED NA

Mucinex® for Treatment of Filamentary Keratitis

NCT02859246

COMPLETED Phase 2

5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts

NCT02705352

COMPLETED Phase 1

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

NCT02592330

TERMINATED Early Phase 1

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

NCT02282917

COMPLETED NA

Computer-Based Auditory Rehabilitation

NCT02147847

TERMINATED Phase 4

The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation

NCT02162433

COMPLETED NA

Use of Amplification in Children With Unilateral Hearing Loss

NCT02269124

COMPLETED Phase 1

Safety and Efficacy of Topical Tacrolimus 0.05% in the Treatment of Ocular Graft-Versus-Host Disease

NCT01977781

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What is open in the Massachusetts Eye and Ear Infirmary pipeline

20 recruiting of 73 indexed (27% open); 36 completed (49%).

Phase mix: 8 late (III/IV) vs 22 early (I/II) (early-phase heavy).

Top condition: Spasmodic Dysphonia (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Massachusetts Eye and Ear Infirmary: open-pipeline peers nationwide

Peers matched on 73 registered trials and 27% open enrollment, not the therapeutic-area sidebar.

Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080 0%10%20%30%40% Total trials Recruiting share Massachusetts Eye and Ear InfirmaryDenver Health and Hospital AuthorityHugo W. Moser Research Institute at Kennedy KriegerJoslin Diabetes CenterTulane UniversityConnecticut Children's Medical CenterCriteriumMinneapolis Heart Institute FoundationNerviano Medical Sciences
Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Massachusetts Eye and Ear Infirmary sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 73 trials (± recruiting share)

Sponsors near 27% open enrollment (± trial volume)

What to do with this Massachusetts Eye and Ear Infirmary page

73 registered trials is a research-attention snapshot, not an endorsement of Massachusetts Eye and Ear Infirmary or any single study.

  • 20 of Massachusetts Eye and Ear Infirmary's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Spasmodic Dysphonia is the condition Massachusetts Eye and Ear Infirmary studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Spasmodic Dysphonia trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Massachusetts Eye and Ear Infirmary pipeline card: 73 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.