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NCT05216770 · ClinicalTrials.gov registry record · Early Phase 1
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
A Early Phase 1 study of Tremor and Laryngeal Dystonia, sponsored by Massachusetts Eye and Ear Infirmary.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 165
- Enrollment target
- 1
- Study location
NCT05216770: Recruiting Early Phase 1 study of Tremor and Laryngeal Dystonia, sponsored by Massachusetts Eye and Ear Infirmary.
NCT05216770 is a Early Phase 1 study of Tremor and Laryngeal Dystonia that is actively recruiting participants, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 165 participants, below the 571-participant average among 10 other Tremor trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05216770, a Early Phase 1 study of Tremor and Laryngeal Dystonia, is actively recruiting participants, sponsored by Massachusetts Eye and Ear Infirmary.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 165 participants
- Enrollment target
- 1
- Study location
Study Summary
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain imaging.
Primary Outcome
Qualitative analysis of brain regions with disorder-specific increases and decreases of spatial (functional MRI) and temporal (MEG and EEG) signals will be determined in patients with laryngeal dystonia compared to patients with voice tremor
Conditions Studied
Interventions
- OTHER Brain imaging
- DRUG Laryngeal sensory block with topical bupivacaine
Study Locations (1)
Massachusetts
- Massachusetts Eye and Ear and University of California San Francisco - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2022-03-24 |
| Est. Completion | 2027-08-31 |
| Phase | Early Phase 1 |
What NCT05216770 shows while recruiting
NCT05216770 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 571-participant average among 10 other Tremor trials with a reported enrollment target (71% lower).
The record links to 3 conditions, with Tremor appearing as the primary indexed condition, and to 2 interventions - of which Brain imaging is the first listed.
NCT05216770 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05216770 about?
NCT05216770 is a clinical study titled "Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor". The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain imaging.
What is the current status of trial NCT05216770?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 165 participants. The study started on 2022-03-24. Estimated completion is 2027-08-31.
What conditions does trial NCT05216770 study?
This clinical trial studies the following conditions: Tremor, Laryngeal Dystonia, Spasmodic Dysphonia.
What interventions are being tested in trial NCT05216770?
The interventions under investigation include: Brain imaging (OTHER), Laryngeal sensory block with topical bupivacaine (DRUG).
Who is sponsoring clinical trial NCT05216770?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05216770 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05216770's enrollment target sits among peer trials
165 4th of 10 higher than 6 of 10 other Tremor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tremor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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