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NCT07383701 · ClinicalTrials.gov registry record · Phase 2
Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema
A Phase 2 study, sponsored by Massachusetts Eye and Ear Infirmary.
- Not yet
- Registry status
- Phase 2
- Development phase
- 36
- Enrollment target
NCT07383701 is a Phase 2 study that has not yet begun recruiting, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 36 participants.
The verdict
NCT07383701, a Phase 2 study, has not yet begun recruiting, sponsored by Massachusetts Eye and Ear Infirmary.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 36 participants
- Enrollment target
Study Summary
This pilot prospective, interventional, longitudinal study, aims to evaluate the potential benefits of the probiotic supplement Lactobacillus plantarum 299v in patients with diabetic macular edema (DME). The study seeks to address the following questions: 1. Does central macular thickness on optical coherence tomography decrease after 4 months of supplementation? 2. Is visual acuity improved at 1, 2, 3, and 4 months following initiation of supplementation? 3. Is the number of anti-VEGF injections reduced following initiation of supplementation? Outcomes will be compared to a control group, using historic retrospective data. Participants will take Lactobacillus plantarum 299v orally twice daily for four months.
Interventions
- DRUG Lactobacillus plantarum 299v
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-08-01 |
| Est. Completion | 2027-09-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07383701
The ClinicalTrials.gov registry entry for NCT07383701 describes a study currently listed as not yet recruiting, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts Eye and Ear Infirmary, which has 73 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Lactobacillus plantarum 299v is the first listed.
NCT07383701 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07383701 about?
NCT07383701 is a clinical study titled "Lactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema". This pilot prospective, interventional, longitudinal study, aims to evaluate the potential benefits of the probiotic supplement Lactobacillus plantarum 299v in patients with diabetic macular edema (DME). The study seeks to address the following questions: 1. Does central macular thickness on optic...
What is the current status of trial NCT07383701?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2026-08-01. Estimated completion is 2027-09-01.
What interventions are being tested in trial NCT07383701?
The interventions under investigation include: Lactobacillus plantarum 299v (DRUG).
Who is sponsoring clinical trial NCT07383701?
This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.
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