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NCT05331664 · ClinicalTrials.gov registry record · Phase 4

Dropless Pars Plana Vitrectomy Study

A Phase 4 study of Rhegmatogenous Retinal Detachment, sponsored by Massachusetts Eye and Ear Infirmary.

Recruiting
Registry status
Phase 4
Development phase
168
Enrollment target
1
Study location

NCT05331664 is a Phase 4 study of Rhegmatogenous Retinal Detachment that is actively recruiting participants, run by Massachusetts Eye and Ear Infirmary. The registered enrollment target is 168 participants, below the 329-participant average among 3 other Rhegmatogenous Retinal Detachment trials with a reported enrollment target (49% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05331664, a Phase 4 study of Rhegmatogenous Retinal Detachment, is actively recruiting participants, sponsored by Massachusetts Eye and Ear Infirmary.

RECRUITING
Registry status
Phase 4
Development phase
168 participants
Enrollment target
1
Study location

Study Summary

To demonstrate that intraoperative use of subtenon triamcinolone acetonide at the time of surgery without postoperative eye drops is non-inferior to the regimen of postoperative eye drops following primary pars plana vitrectomy for retinal detachment.

Interventions

  • DRUG Atropine 1%
  • PROCEDURE Pars plana vitrectomy
  • DRUG Triamcinolone Acetonide 40mg/mL
  • DRUG Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin
  • DRUG Prednisolone 1%

Study Locations (1)

Massachusetts

  • Massachusetts Eye and Ear - Boston

Trial Details

FieldValue
Enrollment Target 168 participants
Start Date 2022-07-25
Est. Completion 2027-01-30
Phase Phase 4

What the Registry Record Tells You About NCT05331664

The ClinicalTrials.gov registry entry for NCT05331664 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 329-participant average among 3 other Rhegmatogenous Retinal Detachment trials with a reported enrollment target (49% lower). The listed sponsor is Massachusetts Eye and Ear Infirmary, which has 73 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Rhegmatogenous Retinal Detachment appearing as the primary indexed condition, and to 5 interventions - of which Atropine 1% is the first listed.

NCT05331664 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05331664 about?

NCT05331664 is a clinical study titled "Dropless Pars Plana Vitrectomy Study". To demonstrate that intraoperative use of subtenon triamcinolone acetonide at the time of surgery without postoperative eye drops is non-inferior to the regimen of postoperative eye drops following primary pars plana vitrectomy for retinal detachment.

What is the current status of trial NCT05331664?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 168 participants. The study started on 2022-07-25. Estimated completion is 2027-01-30.

What conditions does trial NCT05331664 study?

This clinical trial studies the following conditions: Rhegmatogenous Retinal Detachment.

What interventions are being tested in trial NCT05331664?

The interventions under investigation include: Atropine 1% (DRUG), Pars plana vitrectomy (PROCEDURE), Triamcinolone Acetonide 40mg/mL (DRUG), Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin (DRUG), Prednisolone 1% (DRUG).

Who is sponsoring clinical trial NCT05331664?

This trial is sponsored by Massachusetts Eye and Ear Infirmary, which has 73 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05331664 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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